HCSGD entry for UNC5B
1. General information
| Official gene symbol | UNC5B |
|---|---|
| Entrez ID | 219699 |
| Gene full name | unc-5 homolog B (C. elegans) |
| Other gene symbols | UNC5H2 p53RDL1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0014068 | Positive regulation of phosphatidylinositol 3-kinase signaling | IMP | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0033564 | Anterior/posterior axon guidance | IEA | biological_process |
| GO:0042981 | Regulation of apoptotic process | TAS | biological_process |
| GO:0043065 | Positive regulation of apoptotic process | TAS | biological_process |
| GO:0043524 | Negative regulation of neuron apoptotic process | IMP | biological_process |
| GO:2001240 | Negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | IMP | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6178289921 | 0.0744050112 | 0.9999902473 | 0.5141544500 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3426851631 |
| GSE13712_SHEAR | Down | -0.2103450627 |
| GSE13712_STATIC | Up | 0.0793081136 |
| GSE19018 | Up | 0.0550836547 |
| GSE19899_A1 | Up | 0.1174085503 |
| GSE19899_A2 | Down | -0.1534439433 |
| PubMed_21979375_A1 | Down | -0.0438213790 |
| PubMed_21979375_A2 | Down | -0.2958680103 |
| GSE35957 | Down | -0.8578603008 |
| GSE36640 | Down | -0.4391690069 |
| GSE54402 | Down | -0.0198560737 |
| GSE9593 | Up | 0.5516973825 |
| GSE43922 | Up | 0.0478838244 |
| GSE24585 | Down | -0.2006526458 |
| GSE37065 | Down | -0.4401805155 |
| GSE28863_A1 | Up | 0.4765988091 |
| GSE28863_A2 | Down | -0.2627153817 |
| GSE28863_A3 | Down | -0.5882895441 |
| GSE28863_A4 | Down | -0.0611307566 |
| GSE48662 | Up | 0.6527162952 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022434 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040612 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041519 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
