HCSGD entry for FAT1
1. General information
| Official gene symbol | FAT1 |
|---|---|
| Entrez ID | 2195 |
| Gene full name | FAT atypical cadherin 1 |
| Other gene symbols | CDHF7 CDHR8 FAT ME5 hFat1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0005911 | Cell-cell junction | IDA | cellular_component |
| GO:0007015 | Actin filament organization | IEA ISS | biological_process |
| GO:0007155 | Cell adhesion | TAS | biological_process |
| GO:0007156 | Homophilic cell adhesion | IEA | biological_process |
| GO:0007163 | Establishment or maintenance of cell polarity | IEA ISS | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0009653 | Anatomical structure morphogenesis | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016337 | Cell-cell adhesion | ISS | biological_process |
| GO:0016477 | Cell migration | ISS | biological_process |
| GO:0030027 | Lamellipodium | IEA | cellular_component |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0030175 | Filopodium | IEA | cellular_component |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1372146043 | 0.0482966415 | 0.7465121124 | 0.4115048867 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7715537314 |
| GSE13712_SHEAR | Up | 0.5457416208 |
| GSE13712_STATIC | Up | 0.9172503602 |
| GSE19018 | Up | 0.0011638748 |
| GSE19899_A1 | Down | -0.5860603589 |
| GSE19899_A2 | Down | -0.2892225313 |
| PubMed_21979375_A1 | Down | -0.5385212176 |
| PubMed_21979375_A2 | Down | -0.2113214699 |
| GSE35957 | Up | 0.1953200756 |
| GSE36640 | Up | 0.5756589722 |
| GSE54402 | Down | -0.6989565321 |
| GSE9593 | Up | 0.2750693598 |
| GSE43922 | Down | -0.1813669873 |
| GSE24585 | Up | 0.2958493907 |
| GSE37065 | Up | 0.1802460513 |
| GSE28863_A1 | Up | 0.4326088093 |
| GSE28863_A2 | Up | 0.9701888970 |
| GSE28863_A3 | Down | -0.7717118117 |
| GSE28863_A4 | Down | -0.3435997768 |
| GSE48662 | Up | 0.2384424877 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046026 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046601 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT047315 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
