HCSGD entry for USP12
1. General information
| Official gene symbol | USP12 |
|---|---|
| Entrez ID | 219333 |
| Gene full name | ubiquitin specific peptidase 12 |
| Other gene symbols | UBH1 USP12L1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004197 | Cysteine-type endopeptidase activity | IMP | molecular_function |
| GO:0004221 | Ubiquitin thiolesterase activity | IDA TAS | molecular_function |
| GO:0004843 | Ubiquitin-specific protease activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0016579 | Protein deubiquitination | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0036062346 | 0.8733407849 | 0.1626594178 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3677389878 |
| GSE13712_SHEAR | Up | 0.7604851709 |
| GSE13712_STATIC | Up | 0.6213660344 |
| GSE19018 | Down | -0.0916287658 |
| GSE19899_A1 | Up | 0.4830886860 |
| GSE19899_A2 | Up | 0.8915285424 |
| PubMed_21979375_A1 | Up | 1.3976747976 |
| PubMed_21979375_A2 | Up | 0.7194652274 |
| GSE35957 | Up | 0.4355297285 |
| GSE36640 | Up | 0.4333208940 |
| GSE54402 | Up | 1.0710593322 |
| GSE9593 | Down | -0.0024179439 |
| GSE43922 | Up | 0.6819193100 |
| GSE24585 | Up | 0.8212782933 |
| GSE37065 | Up | 0.0234930391 |
| GSE28863_A1 | Down | -0.6365806553 |
| GSE28863_A2 | Down | -0.7979277242 |
| GSE28863_A3 | Up | 0.0033509295 |
| GSE28863_A4 | Down | -0.0800657683 |
| GSE48662 | Down | -0.1630677697 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | MIRT002534 | Microarray//Microarray;Other | Functional MTI (Weak) | 15685193 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024309 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026621 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037403 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1260b | MIMAT0015041 | MIRT052688 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | NA | hsa-miR-373 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
