HCSGD entry for FAP

1. General information

Official gene symbolFAP
Entrez ID2191
Gene full namefibroblast activation protein, alpha
Other gene symbolsDPPIV FAPA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002020Protease bindingIPImolecular_function
GO:0004175Endopeptidase activityIDAmolecular_function
GO:0004222Metalloendopeptidase activityTASmolecular_function
GO:0004252Serine-type endopeptidase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005615Extracellular spaceIDAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0008233Peptidase activityIDA IEAmolecular_function
GO:0008236Serine-type peptidase activityIDA IEA IMP NASmolecular_function
GO:0008239Dipeptidyl-peptidase activityNASmolecular_function
GO:0010716Negative regulation of extracellular matrix disassemblyIDAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneNAScellular_component
GO:0030027LamellipodiumIDAcellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0031258Lamellipodium membraneIEAcellular_component
GO:0042803Protein homodimerization activityNASmolecular_function
GO:0043542Endothelial cell migrationIDAbiological_process
GO:0046983Protein dimerization activityNASmolecular_function
GO:0051917Regulation of fibrinolysisICbiological_process
GO:0071438Invadopodium membraneIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.11151476770.03055732310.68960068120.3301596311

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0677934025
GSE13712_SHEARUp0.1548090163
GSE13712_STATICUp0.0302939609
GSE19018Up0.4277271053
GSE19899_A1Down-0.8264984721
GSE19899_A2Down-1.4479149265
PubMed_21979375_A1Down-1.6611059396
PubMed_21979375_A2Down-1.4222906376
GSE35957Up0.5080875663
GSE36640Down-1.9042047913
GSE54402Up0.3844463174
GSE9593Up0.9465520549
GSE43922Down-0.6676404733
GSE24585Up0.0398729539
GSE37065Up0.2338444791
GSE28863_A1Up0.4724631395
GSE28863_A2Up1.4833120459
GSE28863_A3Down-0.2483016570
GSE28863_A4Down-0.1970626799
GSE48662Down-0.2524975694

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.