HCSGD entry for ALDH1B1
1. General information
| Official gene symbol | ALDH1B1 |
|---|---|
| Entrez ID | 219 |
| Gene full name | aldehyde dehydrogenase 1 family, member B1 |
| Other gene symbols | ALDH5 ALDHX |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004029 | Aldehyde dehydrogenase (NAD) activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005759 | Mitochondrial matrix | IEA | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | NAS | biological_process |
| GO:0006068 | Ethanol catabolic process | IEA | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9593195851 | 0.0018171916 | 0.9999902473 | 0.0819580479 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.2439356103 |
| GSE13712_SHEAR | Up | 0.0191061236 |
| GSE13712_STATIC | Up | 0.3425753932 |
| GSE19018 | Up | 0.0074563029 |
| GSE19899_A1 | Down | -0.1091481901 |
| GSE19899_A2 | Up | 0.3780001395 |
| PubMed_21979375_A1 | Down | -0.5979170666 |
| PubMed_21979375_A2 | Down | -0.0575951089 |
| GSE35957 | Up | 0.6290057489 |
| GSE36640 | Down | -0.8968674921 |
| GSE54402 | Down | -0.2625650844 |
| GSE9593 | Down | -0.7507492431 |
| GSE43922 | Down | -0.0342956395 |
| GSE24585 | Down | -1.2783412206 |
| GSE37065 | Down | -0.6277972287 |
| GSE28863_A1 | Down | -0.1575669486 |
| GSE28863_A2 | Down | -0.9837412670 |
| GSE28863_A3 | Down | -0.3116810015 |
| GSE28863_A4 | Down | -0.2093037509 |
| GSE48662 | Down | -0.5365319110 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1226-3p | MIMAT0005577 | MIRT036506 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-130b-5p | MIMAT0004680 | MIRT038303 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040428 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043826 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99b-5p | MIMAT0000689 | MIRT044175 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045046 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
