HCSGD entry for FANCA
1. General information
| Official gene symbol | FANCA |
|---|---|
| Entrez ID | 2175 |
| Gene full name | Fanconi anemia, complementation group A |
| Other gene symbols | FA FA-H FA1 FAA FACA FAH FANCH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006281 | DNA repair | TAS | biological_process |
| GO:0006461 | Protein complex assembly | TAS | biological_process |
| GO:0007140 | Male meiosis | IEA | biological_process |
| GO:0008584 | Male gonad development | IEA | biological_process |
| GO:0008585 | Female gonad development | IEA | biological_process |
| GO:0042127 | Regulation of cell proliferation | IEA | biological_process |
| GO:0043240 | Fanconi anaemia nuclear complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9727087611 | 0.0377830630 | 0.9999902473 | 0.3664513812 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0878754064 |
| GSE13712_SHEAR | Down | -0.2073243346 |
| GSE13712_STATIC | Down | -0.3128040674 |
| GSE19018 | Down | -0.0112518835 |
| GSE19899_A1 | Down | -0.0060122592 |
| GSE19899_A2 | Down | -0.4577231852 |
| PubMed_21979375_A1 | Down | -0.3893232994 |
| PubMed_21979375_A2 | Down | -0.4564890572 |
| GSE35957 | Down | -0.2629600868 |
| GSE36640 | Down | -1.1735594233 |
| GSE54402 | Down | -0.1127142820 |
| GSE9593 | Down | -0.0356518110 |
| GSE43922 | Down | -0.2279588281 |
| GSE24585 | Up | 0.0139304522 |
| GSE37065 | Down | -0.2410022345 |
| GSE28863_A1 | Down | -0.0559211479 |
| GSE28863_A2 | Up | 0.5280917958 |
| GSE28863_A3 | Down | -0.0879015771 |
| GSE28863_A4 | Up | 0.0711360680 |
| GSE48662 | Down | -0.6772829365 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016287 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050966 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
