HCSGD entry for F11

1. General information

Official gene symbolF11
Entrez ID2160
Gene full namecoagulation factor XI
Other gene symbolsFXI
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004252Serine-type endopeptidase activityIEA NASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIEA NAS TAScellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0007596Blood coagulationIEA NAS TASbiological_process
GO:0007597Blood coagulation, intrinsic pathwayTASbiological_process
GO:0008201Heparin bindingIEAmolecular_function
GO:0016020MembraneNAScellular_component
GO:0030193Regulation of blood coagulationIEAbiological_process
GO:0031639Plasminogen activationIDAbiological_process
GO:0051919Positive regulation of fibrinolysisIDAbiological_process
GO:0070009Serine-type aminopeptidase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.78269742790.87140523160.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0291113163
GSE13712_SHEARDown-0.0488828652
GSE13712_STATICDown-0.0810619340
GSE19018Up0.0175524841
GSE19899_A1Up0.0237653811
GSE19899_A2Up0.0928903781
PubMed_21979375_A1Up0.2391700968
PubMed_21979375_A2Up0.0039914992
GSE35957Up0.1083303309
GSE36640Down-0.0022068117
GSE54402Down-0.0133621033
GSE9593Up0.1177996992
GSE43922Up0.0113561598
GSE24585Down-0.1909949668
GSE37065Up0.0234153203
GSE28863_A1Down-0.1082820248
GSE28863_A2Up0.1263892813
GSE28863_A3Up0.0974176566
GSE28863_A4Up0.0823896263
GSE48662Up0.0969727890

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Coagulation Factor IX (Recombinant)DB00100 BTD00038 | BIOD00038
3-HYDROXYPROPYL 3-[({7-[AMINO(IMINO)METHYL]-1-NAPHTHYL}AMINO)CARBONYL]BENZENESULFONATEDB07022 -
(1R)-2-{[AMINO(IMINO)METHYL]AMINO}-1-{4-[(4R)-4-(HYDROXYMETHYL)-1,3,2-DIOXABOROLAN-2-YL]PHENYL}ETHYL NICOTINATEDB07023 -
(R)-1-(4-(4-(HYDROXYMETHYL)-1,3,2-DIOXABOROLAN-2-YL)PHENETHYL)GUANIDINEDB07071 -
6-CARBAMIMIDOYL-4-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-NAPHTHALENE-2-CARBOXYLIC ACID METHYL ESTERDB07074 -
(R)-1-(4-(4-(HYDROXYMETHYL)-1,3,2-DIOXABOROLAN-2-YL)PHENYL)GUANIDINEDB07077 -
N-(7-CARBAMIMIDOYL-NAPHTHALEN-1-YL)-3-HYDROXY-2-METHYL-BENZAMIDEDB07212 -
4-METHYL-PENTANOIC ACID {1-[4-GUANIDINO-1-(THIAZOLE-2-CARBONYL)-BUTYLCARBAMOYL]-2-METHYL-PROPYL}-AMIDEDB07299 -
(R)-1-(4-(4-(HYDROXYMETHYL)-1,3,2-DIOXABOROLAN-2-YL)BENZYL)GUANIDINEDB07887 -
C1 Esterase Inhibitor (Recombinant)DB09228 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.