HCSGD entry for F9


1. General information

Official gene symbolF9
Entrez ID2158
Gene full namecoagulation factor IX
Other gene symbolsFIX HEMB P19 PTC THPH8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004252Serine-type endopeptidase activityIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005576Extracellular regionNAS TAScellular_component
GO:0005788Endoplasmic reticulum lumenTAScellular_component
GO:0005796Golgi lumenTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006508ProteolysisTASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0007597Blood coagulation, intrinsic pathwayTASbiological_process
GO:0007598Blood coagulation, extrinsic pathwayTASbiological_process
GO:0017187Peptidyl-glutamic acid carboxylationTASbiological_process
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82891016300.53852349830.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1099035398
GSE13712_SHEARDown-0.3029755806
GSE13712_STATICDown-0.1499932224
GSE19018Up0.0224666527
GSE19899_A1Up0.0869357776
GSE19899_A2Down-0.0621003799
PubMed_21979375_A1Down-0.1468526156
PubMed_21979375_A2Down-0.0789831295
GSE35957Up0.0567133116
GSE36640Up0.0341625001
GSE54402Up0.1226787236
GSE9593Up0.1495813054
GSE43922Up0.0137196001
GSE24585Up0.0730182398
GSE37065Down-0.0339837315
GSE28863_A1Up0.0294238440
GSE28863_A2Down-0.0285964550
GSE28863_A3Up0.0235141421
GSE28863_A4Up0.0287201969
GSE48662Down-0.0439509022

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

MenadioneDB00170 NUTR00062
TTP889DB05131 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

25826898Senescence marker (p16INK4a) and disc degeneration markers [A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS 5), Aggrecan, and Sry-related HMG box transcription factor 9 (Sox-9)] were determined in the NP specimens with immunohistochemistry and Western blot
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