HCSGD entry for F7

1. General information

Official gene symbolF7
Entrez ID2155
Gene full namecoagulation factor VII (serum prothrombin conversion accelerator)
Other gene symbolsSPCA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001948Glycoprotein bindingIPImolecular_function
GO:0002690Positive regulation of leukocyte chemotaxisIDAbiological_process
GO:0004252Serine-type endopeptidase activityIEAmolecular_function
GO:0005102Receptor bindingIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0005788Endoplasmic reticulum lumenTAScellular_component
GO:0005796Golgi lumenTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006508ProteolysisIEA TASbiological_process
GO:0007596Blood coagulationIEA TASbiological_process
GO:0007598Blood coagulation, extrinsic pathwayTASbiological_process
GO:0007623Circadian rhythmIEAbiological_process
GO:0008236Serine-type peptidase activityTASmolecular_function
GO:0010641Positive regulation of platelet-derived growth factor receptor signaling pathwayIDAbiological_process
GO:0017187Peptidyl-glutamic acid carboxylationTASbiological_process
GO:0030194Positive regulation of blood coagulationIEAbiological_process
GO:0030335Positive regulation of cell migrationTASbiological_process
GO:0031100Organ regenerationIEAbiological_process
GO:0031982VesicleIEAcellular_component
GO:0032571Response to vitamin KIEAbiological_process
GO:0043627Response to estrogenIEAbiological_process
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0050927Positive regulation of positive chemotaxisIDAbiological_process
GO:0051897Positive regulation of protein kinase B signalingIDAbiological_process
GO:0060416Response to growth hormoneIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.52753570530.90179010680.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0595185097
GSE13712_SHEARDown-0.0325629867
GSE13712_STATICUp0.2273278247
GSE19018Down-0.0454615955
GSE19899_A1Up0.1417763185
GSE19899_A2Up0.0145320991
PubMed_21979375_A1Up0.1548536065
PubMed_21979375_A2Down-0.1108085094
GSE35957Up0.2574531694
GSE36640Up0.0545990041
GSE54402Up0.0220961523
GSE9593Up0.0730389009
GSE43922Up0.0259171948
GSE24585Up0.0221217112
GSE37065Down-0.0935702285
GSE28863_A1Up0.0026504939
GSE28863_A2Down-0.1839996948
GSE28863_A3Up0.3439734199
GSE28863_A4Up0.1307588261
GSE48662Down-0.0237363593

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Coagulation factor VIIa Recombinant HumanDB00036 BTD00006 | BIOD00006
Coagulation Factor IX (Recombinant)DB00100 BTD00038 | BIOD00038
MenadioneDB00170 NUTR00062
(2R)-({4-[AMINO(IMINO)METHYL]PHENYL}AMINO){5-ETHOXY-2-FLUORO-3-[(3R)-TETRAHYDROFURAN-3-YLOXY]PHENYL}ACETICACIDDB04590 -
3-({1-[3-CARBAMIMIDOYL-1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-PROPYLCARBAMOYL]-2-METHYL-BUTYLSULFAMOYL}-METHYL)-BENZOIC ACIDDB04593 -
2-[2-ETHANESULFONYLAMINO-3-(5-PROPOXY-1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE)DB04606 -
2-[2-ETHANESULFONYLAMINO-3-(1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIM IDOYL-BENZYLAMIDE)DB04758 -
N-[1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-3-METHYLSULFANYL-PROPYL]-3-HYDROXY-2-PROPOXYAMINO-BUTYRAMIDDB04767 -
2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINEDB07207 -
[2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREADB07247 -
5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID)DB07376 -
{5-(5-AMINO-1H-PYRROLO[3,2-B]PYRIDIN-2-YL)-6-HYDROXY-3'-NITRO-BIPHENYL-3-YL]-ACETIC ACIDDB08232 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.