HCSGD entry for ABCD1

1. General information

Official gene symbolABCD1
Entrez ID215
Gene full nameATP-binding cassette, sub-family D (ALD), member 1
Other gene symbolsABC42 ALD ALDP AMN
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005215Transporter activityNASmolecular_function
GO:0005325Peroxisomal fatty-acyl-CoA transporter activityIGI TASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIDA IEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0005777PeroxisomeIDAcellular_component
GO:0005778Peroxisomal membraneIDA TAScellular_component
GO:0005779Integral component of peroxisomal membraneIDA NAScellular_component
GO:0005829CytosolTAScellular_component
GO:0006200ATP catabolic processIDA NASbiological_process
GO:0006635Fatty acid beta-oxidationIDA IGIbiological_process
GO:0006810TransportIEAbiological_process
GO:0007031Peroxisome organizationIDA NASbiological_process
GO:0015910Peroxisomal long-chain fatty acid importIGIbiological_process
GO:0015916Fatty-acyl-CoA transportIGI TASbiological_process
GO:0015919Peroxisomal membrane transportNASbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016887ATPase activityIDA IEAmolecular_function
GO:0019899Enzyme bindingIPImolecular_function
GO:0033540Fatty acid beta-oxidation using acyl-CoA oxidaseTASbiological_process
GO:0033559Unsaturated fatty acid metabolic processTASbiological_process
GO:0036109Alpha-linolenic acid metabolic processTASbiological_process
GO:0042626ATPase activity, coupled to transmembrane movement of substancesNASmolecular_function
GO:0042758Long-chain fatty acid catabolic processIGIbiological_process
GO:0042760Very long-chain fatty acid catabolic processIDA IGIbiological_process
GO:0042802Identical protein bindingIPImolecular_function
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0043651Linoleic acid metabolic processTASbiological_process
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03328016790.72300401200.41908708751.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1257243443
GSE13712_SHEARUp0.2003757114
GSE13712_STATICUp0.4671860860
GSE19018Up0.1381306329
GSE19899_A1Up0.0128516242
GSE19899_A2Up0.1134638129
PubMed_21979375_A1Up0.9436756988
PubMed_21979375_A2Up0.8570676575
GSE35957Up0.3284547845
GSE36640Up0.3866157209
GSE54402Down-0.0272566122
GSE9593Up0.1799003754
GSE43922Up0.5104818376
GSE24585Down-0.0921201879
GSE37065Up0.2643871636
GSE28863_A1Down-0.3841580488
GSE28863_A2Down-0.5576901726
GSE28863_A3Up0.2747768103
GSE28863_A4Down-0.0936205890
GSE48662Up0.2742030164

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029416MicroarrayFunctional MTI (Weak)19088304
hsa-miR-615-3pMIMAT0003283MIRT039787CLASHFunctional MTI (Weak)23622248
hsa-miR-23a-3pMIMAT0000078MIRT050424CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.