HCSGD entry for EYA2

1. General information

Official gene symbolEYA2
Entrez ID2139
Gene full nameeyes absent homolog 2 (Drosophila)
Other gene symbolsEAB1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000287Magnesium ion bindingIDAmolecular_function
GO:0004725Protein tyrosine phosphatase activityIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0006281DNA repairIEAbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007501Mesodermal cell fate specificationTASbiological_process
GO:0014706Striated muscle tissue developmentIEAbiological_process
GO:0016576Histone dephosphorylationIDAbiological_process
GO:0035335Peptidyl-tyrosine dephosphorylationIDAbiological_process
GO:0097192Extrinsic apoptotic signaling pathway in absence of ligandIEAbiological_process
GO:0097345Mitochondrial outer membrane permeabilizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96015283990.01364681430.99999024730.2299335253

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0709018863
GSE13712_SHEARUp0.0970590716
GSE13712_STATICDown-0.0427160216
GSE19018Down-0.3514855055
GSE19899_A1Down-0.3001270528
GSE19899_A2Down-0.5727820861
PubMed_21979375_A1Down-2.1104007594
PubMed_21979375_A2Down-0.7511615147
GSE35957Down-0.7128537871
GSE36640Down-1.0880543922
GSE54402Down-0.5503208917
GSE9593Down-0.7941452528
GSE43922Down-0.0545887104
GSE24585Down-0.0896091669
GSE37065Down-0.0594482862
GSE28863_A1Up0.1207415018
GSE28863_A2Down-0.1235902188
GSE28863_A3Up0.1400264990
GSE28863_A4Up0.0372560404
GSE48662Up0.2358235083

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.