HCSGD entry for EYA1

1. General information

Official gene symbolEYA1
Entrez ID2138
Gene full nameeyes absent homolog 1 (Drosophila)
Other gene symbolsBOP BOR BOS1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000132Establishment of mitotic spindle orientationIEAbiological_process
GO:0001656Metanephros developmentIEAbiological_process
GO:0001658Branching involved in ureteric bud morphogenesisIEAbiological_process
GO:0003151Outflow tract morphogenesisIEAbiological_process
GO:0003723RNA bindingIEAmolecular_function
GO:0004725Protein tyrosine phosphatase activityIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006302Double-strand break repairIMPbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007389Pattern specification processIEAbiological_process
GO:0007605Sensory perception of soundTASbiological_process
GO:0009653Anatomical structure morphogenesisTASbiological_process
GO:0010212Response to ionizing radiationIDAbiological_process
GO:0014706Striated muscle tissue developmentIEAbiological_process
GO:0016576Histone dephosphorylationIDAbiological_process
GO:0016925Protein sumoylationISSbiological_process
GO:0034613Cellular protein localizationIEAbiological_process
GO:0035088Establishment or maintenance of apical/basal cell polarityIEAbiological_process
GO:0035909Aorta morphogenesisIEAbiological_process
GO:0042471Ear morphogenesisIEAbiological_process
GO:0042473Outer ear morphogenesisIEAbiological_process
GO:0042474Middle ear morphogenesisIEAbiological_process
GO:0045664Regulation of neuron differentiationIEAbiological_process
GO:0045739Positive regulation of DNA repairIMPbiological_process
GO:0045747Positive regulation of Notch signaling pathwayIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048665Neuron fate specificationIEAbiological_process
GO:0048704Embryonic skeletal system morphogenesisIEAbiological_process
GO:0048752Semicircular canal morphogenesisIEAbiological_process
GO:0050679Positive regulation of epithelial cell proliferationIEAbiological_process
GO:0060037Pharyngeal system developmentIEAbiological_process
GO:0060487Lung epithelial cell differentiationIEAbiological_process
GO:0071600Otic vesicle morphogenesisIEAbiological_process
GO:0072513Positive regulation of secondary heart field cardioblast proliferationIEAbiological_process
GO:0090103Cochlea morphogenesisIEAbiological_process
GO:2001240Negative regulation of extrinsic apoptotic signaling pathway in absence of ligandIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.44547880780.20456498230.99999024730.8766452133

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0446082461
GSE13712_SHEARUp0.0260856236
GSE13712_STATICUp0.0328560887
GSE19018Down-0.1709782764
GSE19899_A1Up0.1884256199
GSE19899_A2Down-0.0271952437
PubMed_21979375_A1Down-0.0944228630
PubMed_21979375_A2Down-0.0069278550
GSE35957Up0.2989566196
GSE36640Up0.0308809930
GSE54402Up0.0379671796
GSE9593Down-0.0264818772
GSE43922Up0.0115638150
GSE24585Down-1.1242201749
GSE37065Up0.4296359931
GSE28863_A1Down-0.0590002693
GSE28863_A2Down-0.0909445021
GSE28863_A3Up0.1139127331
GSE28863_A4Up0.0074601043
GSE48662Down-0.0078064574

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-562MIMAT0003226MIRT000035Luciferase reporter assayFunctional MTI19789318
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.