HCSGD entry for EXTL2
1. General information
| Official gene symbol | EXTL2 |
|---|---|
| Entrez ID | 2135 |
| Gene full name | exostosin-like glycosyltransferase 2 |
| Other gene symbols | EXTR2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001888 | Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity | IDA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0006044 | N-acetylglucosamine metabolic process | IDA IEA | biological_process |
| GO:0015012 | Heparan sulfate proteoglycan biosynthetic process | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016758 | Transferase activity, transferring hexosyl groups | IEA | molecular_function |
| GO:0019276 | UDP-N-acetylgalactosamine metabolic process | IDA | biological_process |
| GO:0031227 | Intrinsic component of endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0035248 | Alpha-1,4-N-acetylgalactosaminyltransferase activity | IDA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2096441169 | 0.2501644656 | 0.8821811031 | 0.9602710952 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2845060394 |
| GSE13712_SHEAR | Down | -0.2727006886 |
| GSE13712_STATIC | Up | 0.0694597723 |
| GSE19018 | Down | -0.2081153715 |
| GSE19899_A1 | Up | 0.7262279977 |
| GSE19899_A2 | Down | -0.0838758350 |
| PubMed_21979375_A1 | Up | 0.6765948632 |
| PubMed_21979375_A2 | Up | 0.4372063173 |
| GSE35957 | Down | -0.6324116095 |
| GSE36640 | Up | 0.4494068411 |
| GSE54402 | Down | -0.4032008365 |
| GSE9593 | Down | -0.1663777558 |
| GSE43922 | Up | 0.5547670244 |
| GSE24585 | Up | 0.1109477068 |
| GSE37065 | Down | -0.1455455583 |
| GSE28863_A1 | Down | -0.0556105440 |
| GSE28863_A2 | Up | 0.3011073555 |
| GSE28863_A3 | Down | -0.9752757313 |
| GSE28863_A4 | Down | -0.1092755828 |
| GSE48662 | Down | -0.0940682225 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Uridine-Diphosphate-N-Acetylgalactosamine | DB02196 | EXPT03169 |
| Uridine-Diphosphate-N-Acetylglucosamine | DB03397 | EXPT03168 |
| Uridine-5'-Diphosphate | DB03435 | EXPT03172 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024420 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026802 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
