HCSGD entry for EVC


1. General information

Official gene symbolEVC
Entrez ID2121
Gene full nameEllis van Creveld syndrome
Other gene symbolsDWF-1 EVC1 EVCL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001501Skeletal system developmentTASbiological_process
GO:0003416Endochondral bone growthISSbiological_process
GO:0005737CytoplasmIEAcellular_component
GO:0005929CiliumIDAcellular_component
GO:0007224Smoothened signaling pathwayIEAbiological_process
GO:0007517Muscle organ developmentTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0036064Ciliary basal bodyISScellular_component
GO:0045880Positive regulation of smoothened signaling pathwayISSbiological_process
GO:0051216Cartilage developmentIEAbiological_process
GO:0060170Ciliary membraneIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03777738310.87205149120.43861424791.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1551482506
GSE13712_SHEARUp0.4483996690
GSE13712_STATICUp0.3210378497
GSE19018Up0.0841093304
GSE19899_A1Down-0.2146962729
GSE19899_A2Up0.0509199313
PubMed_21979375_A1Down-0.0481538393
PubMed_21979375_A2Down-0.1580889454
GSE35957Up0.4359967758
GSE36640Up0.5386735860
GSE54402Down-0.2168865872
GSE9593Up0.7913653527
GSE43922Down-0.2087576363
GSE24585Down-0.0678559530
GSE37065Down-0.0430726311
GSE28863_A1Up1.0745394236
GSE28863_A2Up0.8985242074
GSE28863_A3Up0.2225448456
GSE28863_A4Down-0.1672095895
GSE48662Up0.2513994822

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018424MicroarrayFunctional MTI (Weak)18185580
hsa-miR-455-3pMIMAT0004784MIRT037807CLASHFunctional MTI (Weak)23622248
hsa-miR-339-5pMIMAT0000764MIRT042772CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.