HCSGD entry for EYA4


1. General information

Official gene symbolEYA4
Entrez ID2070
Gene full nameeyes absent homolog 4 (Drosophila)
Other gene symbolsCMD1J DFNA10
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004725Protein tyrosine phosphatase activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006281DNA repairIEAbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007601Visual perceptionTASbiological_process
GO:0007605Sensory perception of soundIEAbiological_process
GO:0009653Anatomical structure morphogenesisTASbiological_process
GO:0016568Chromatin modificationIEAbiological_process
GO:0042474Middle ear morphogenesisIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048839Inner ear developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.19006089050.22851121540.84789706780.9206014375

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1229074104
GSE13712_SHEARUp0.0833212745
GSE13712_STATICDown-0.1398271482
GSE19018Up0.0455635085
GSE19899_A1Down-0.0164077624
GSE19899_A2Down-0.1963408881
PubMed_21979375_A1Up0.8575012012
PubMed_21979375_A2Up0.9221730299
GSE35957Down-0.1035561339
GSE36640Up0.0418343529
GSE54402Up0.2387419072
GSE9593Up0.0272538778
GSE43922Up0.3948159610
GSE24585Down-1.0411141451
GSE37065Down-0.1305393013
GSE28863_A1Down-0.0652622481
GSE28863_A2Up0.0065272052
GSE28863_A3Up0.0749835118
GSE28863_A4Down-0.0452150048
GSE48662Down-0.1865043692

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT002568Microarray//Microarray;OtherFunctional MTI (Weak)15685193
hsa-miR-203aMIMAT0000264MIRT005750Immunofluorescence//In situ hybridization//Luciferase reporter assay//Northern blot//qRT-PCR//Western blotFunctional MTI20827281
hsa-miR-27b-3pMIMAT0000419MIRT005754Immunofluorescence//In situ hybridization//Luciferase reporter assay//Northern blot//qRT-PCR//Western blotFunctional MTI20827281
hsa-miR-224-5pMIMAT0000281MIRT005755Immunofluorescence//In situ hybridization//Luciferase reporter assay//Northern blot//qRT-PCR//Western blotFunctional MTI20827281
hsa-miR-148b-3pMIMAT0000759MIRT019463MicroarrayFunctional MTI (Weak)17612493
hsa-miR-132-3pMIMAT0000426MIRT021837MicroarrayFunctional MTI (Weak)17612493
hsa-miR-128-3pMIMAT0000424MIRT022072MicroarrayFunctional MTI (Weak)17612493
hsa-miR-122-5pMIMAT0000421MIRT023358MicroarrayFunctional MTI (Weak)17612493
hsa-miR-181a-5pMIMAT0000256MIRT025147MicroarrayFunctional MTI (Weak)17612493
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.