HCSGD entry for EPS15

1. General information

Official gene symbolEPS15
Entrez ID2060
Gene full nameepidermal growth factor receptor pathway substrate 15
Other gene symbolsAF-1P AF1P MLLT5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005905Coated pitTAScellular_component
GO:0006897EndocytosisIEAbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0015031Protein transportIEAbiological_process
GO:0016050Vesicle organizationTASbiological_process
GO:0017124SH3 domain bindingIEAmolecular_function
GO:0030122AP-2 adaptor complexIEAcellular_component
GO:0031901Early endosome membraneIEAcellular_component
GO:0032456Endocytic recyclingICbiological_process
GO:0042059Negative regulation of epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0042802Identical protein bindingIEAmolecular_function
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0048268Clathrin coat assemblyIDAbiological_process
GO:0060170Ciliary membraneIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.45706861440.16043782530.99999024730.7737216508

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3031064629
GSE13712_SHEARUp0.1423683193
GSE13712_STATICUp0.0169576069
GSE19018Up0.4374338631
GSE19899_A1Down-0.3455056684
GSE19899_A2Down-0.2222925173
PubMed_21979375_A1Down-0.0202508321
PubMed_21979375_A2Down-0.0088846836
GSE35957Up0.3789908110
GSE36640Up0.3119342168
GSE54402Down-0.4510427137
GSE9593Up0.3998525898
GSE43922Down-0.0500510946
GSE24585Up0.2470720121
GSE37065Up0.1465793403
GSE28863_A1Down-0.1683500953
GSE28863_A2Up0.1501622836
GSE28863_A3Down-0.8895404157
GSE28863_A4Down-0.3093791871
GSE48662Up0.4934744272

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.