HCSGD entry for AK4
1. General information
| Official gene symbol | AK4 |
|---|---|
| Entrez ID | 205 |
| Gene full name | adenylate kinase 4 |
| Other gene symbols | AK 4 AK3 AK3L1 AK3L2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001889 | Liver development | IEA | biological_process |
| GO:0004017 | Adenylate kinase activity | IDA IEA | molecular_function |
| GO:0004550 | Nucleoside diphosphate kinase activity | IDA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005759 | Mitochondrial matrix | IEA ISS | cellular_component |
| GO:0006165 | Nucleoside diphosphate phosphorylation | IDA | biological_process |
| GO:0007420 | Brain development | IEA | biological_process |
| GO:0009142 | Nucleoside triphosphate biosynthetic process | IDA | biological_process |
| GO:0042493 | Response to drug | IEA | biological_process |
| GO:0046033 | AMP metabolic process | IDA | biological_process |
| GO:0046034 | ATP metabolic process | IDA | biological_process |
| GO:0046039 | GTP metabolic process | IDA | biological_process |
| GO:0046899 | Nucleoside triphosphate adenylate kinase activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0017897344 | 0.8871676912 | 0.1123130952 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.0582638960 |
| GSE13712_SHEAR | Up | 0.6524620527 |
| GSE13712_STATIC | Up | 1.0222359027 |
| GSE19018 | Up | 1.8909961234 |
| GSE19899_A1 | Up | 0.2747424666 |
| GSE19899_A2 | Up | 0.9175190456 |
| PubMed_21979375_A1 | Up | 1.7752918439 |
| PubMed_21979375_A2 | Up | 2.1583538965 |
| GSE35957 | Up | 0.4332713281 |
| GSE36640 | Up | 0.1605997231 |
| GSE54402 | Down | -0.3408481747 |
| GSE9593 | Up | 0.9114419639 |
| GSE43922 | Up | 0.5511278725 |
| GSE24585 | Down | -0.1390340711 |
| GSE37065 | Down | -0.0198210233 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.3570586382 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030106 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030613 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
