HCSGD entry for EPHB1

1. General information

Official gene symbol	EPHB1
Entrez ID	2047
Gene full name	EPH receptor B1
Other gene symbols	ELK EPHT2 Hek6 NET
Links to Entrez Gene	Links to Entrez Gene

2. Neighbors in the network

This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID	GO term	Evidence	Category
GO:0001525	Angiogenesis	IDA	biological_process
GO:0004713	Protein tyrosine kinase activity	IEA	molecular_function
GO:0005003	Ephrin receptor activity	IEA	molecular_function
GO:0005005	Transmembrane-ephrin receptor activity	IDA	molecular_function
GO:0005515	Protein binding	IPI	molecular_function
GO:0005524	ATP binding	IEA	molecular_function
GO:0005737	Cytoplasm	IEA	cellular_component
GO:0005887	Integral component of plasma membrane	IDA	cellular_component
GO:0007411	Axon guidance	ISS	biological_process
GO:0008046	Axon guidance receptor activity	IEA	molecular_function
GO:0016021	Integral component of membrane	IEA	cellular_component
GO:0018108	Peptidyl-tyrosine phosphorylation	IDA	biological_process
GO:0021631	Optic nerve morphogenesis	IEA	biological_process
GO:0021952	Central nervous system projection neuron axonogenesis	IEA ISS	biological_process
GO:0022008	Neurogenesis	ISS	biological_process
GO:0030010	Establishment of cell polarity	IEA ISS	biological_process
GO:0030424	Axon	IEA	cellular_component
GO:0030425	Dendrite	IEA	cellular_component
GO:0031290	Retinal ganglion cell axon guidance	IEA ISS	biological_process
GO:0031589	Cell-substrate adhesion	IDA	biological_process
GO:0031901	Early endosome membrane	IDA	cellular_component
GO:0045121	Membrane raft	IEA	cellular_component
GO:0046328	Regulation of JNK cascade	IDA	biological_process
GO:0046777	Protein autophosphorylation	IDA IEA	biological_process
GO:0048013	Ephrin receptor signaling pathway	IDA IEA	biological_process
GO:0048593	Camera-type eye morphogenesis	IEA	biological_process
GO:0050965	Detection of temperature stimulus involved in sensory perception of pain	IEA ISS	biological_process
GO:0051965	Positive regulation of synapse assembly	IEA ISS	biological_process
GO:0060326	Cell chemotaxis	IDA IEA	biological_process
GO:0060996	Dendritic spine development	ISS	biological_process
GO:0060997	Dendritic spine morphogenesis	IEA ISS	biological_process
GO:0061351	Neural precursor cell proliferation	IEA ISS	biological_process
GO:0070372	Regulation of ERK1 and ERK2 cascade	IDA	biological_process

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4. Expression levels in datasets

Meta-analysis result

p-value up	p-value down	FDR up	FDR down
0.1864095589	0.5799659663	0.8423151931	1.0000000000

Individual experiment result
( "-" represent NA in the specific microarray platform )

Data source	Up or down	Log fold change
GSE11954	Up	0.6023568975
GSE13712_SHEAR	Down	-0.4081187413
GSE13712_STATIC	Down	-0.8399680711
GSE19018	Up	0.0396344832
GSE19899_A1	Up	0.0485761229
GSE19899_A2	Down	-0.0866308149
PubMed_21979375_A1	Up	0.2734328467
PubMed_21979375_A2	Up	0.1610211068
GSE35957	Down	-0.0906132744
GSE36640	Down	-0.0456861446
GSE54402	Up	0.8319285990
GSE9593	Up	0.0417605621
GSE43922	Up	0.0212561550
GSE24585	Up	0.5094032113
GSE37065	Up	0.4994130728
GSE28863_A1	Down	-0.1962324873
GSE28863_A2	Down	-0.1922985386
GSE28863_A3	Up	0.1837079927
GSE28863_A4	Down	-0.0682129683
GSE48662	Down	-0.2347567183

5. Regulation relationships with compounds/drugs/microRNAs

Compounds

Not regulated by compounds

Drugs

Not regulated by drugs

MicroRNAs

mirTarBase

No target information from mirTarBase

mirRecord

No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.

Navigator

1.General information
2.Neighbors in the network
3.Gene Ontology Annotation
4.Expression levels
5.Regulation
6.Text-mining results