HCSGD entry for EPHA5

1. General information

Official gene symbolEPHA5
Entrez ID2044
Gene full nameEPH receptor A5
Other gene symbolsCEK7 EHK1 HEK7 TYRO4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005003Ephrin receptor activityIEA ISSmolecular_function
GO:0005004GPI-linked ephrin receptor activityISSmolecular_function
GO:0005005Transmembrane-ephrin receptor activityNASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005791Rough endoplasmic reticulumIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0007411Axon guidanceISSbiological_process
GO:0009897External side of plasma membraneIDAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0018108Peptidyl-tyrosine phosphorylationISS NASbiological_process
GO:0019933CAMP-mediated signalingISSbiological_process
GO:0021766Hippocampus developmentISSbiological_process
GO:0030424AxonIEAcellular_component
GO:0030425DendriteIDAcellular_component
GO:0032314Regulation of Rac GTPase activityISSbiological_process
GO:0032793Positive regulation of CREB transcription factor activityISSbiological_process
GO:0032956Regulation of actin cytoskeleton organizationISSbiological_process
GO:0043025Neuronal cell bodyIDAcellular_component
GO:0048013Ephrin receptor signaling pathwayISSbiological_process
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
GO:0048666Neuron developmentIEPbiological_process
GO:0051964Negative regulation of synapse assemblyIEAbiological_process
GO:0061178Regulation of insulin secretion involved in cellular response to glucose stimulusISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.59243006340.24547034310.99999024730.9535160714

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.7655278826
GSE13712_SHEARDown-0.1612946675
GSE13712_STATICDown-0.2933623873
GSE19018Up0.0449446532
GSE19899_A1Up0.0043975002
GSE19899_A2Up0.0495966711
PubMed_21979375_A1Down-0.2097989636
PubMed_21979375_A2Up0.2230454782
GSE35957Up2.0515621285
GSE36640Down-0.0505607029
GSE54402Up0.0812693566
GSE9593Down-0.0210657125
GSE43922Up0.1245945291
GSE24585Down-0.1323290072
GSE37065Down-0.1490707335
GSE28863_A1Down-0.1915119248
GSE28863_A2Up0.0215372529
GSE28863_A3Up0.1987847718
GSE28863_A4Down-0.1259449422
GSE48662Down-0.1290940102

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-34a-5pMIMAT0000255MIRT006576Luciferase reporter assay//Western blotFunctional MTI22079638
hsa-miR-181a-5pMIMAT0000256MIRT025144MicroarrayFunctional MTI (Weak)17612493
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-34a-5pMIMAT0000255NAhsa-miR-34a{Western blot}{downregulation}22079638
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.