HCSGD entry for HTRA4
1. General information
| Official gene symbol | HTRA4 |
|---|---|
| Entrez ID | 203100 |
| Gene full name | HtrA serine peptidase 4 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001558 | Regulation of cell growth | IEA | biological_process |
| GO:0004175 | Endopeptidase activity | IDA | molecular_function |
| GO:0004252 | Serine-type endopeptidase activity | IEA | molecular_function |
| GO:0005520 | Insulin-like growth factor binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0006508 | Proteolysis | IDA | biological_process |
| GO:0030512 | Negative regulation of transforming growth factor beta receptor signaling pathway | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7564748604 | 0.1975286007 | 0.9999902473 | 0.8599953200 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1522399201 |
| GSE13712_SHEAR | Down | -0.3468452037 |
| GSE13712_STATIC | Up | 0.1851413191 |
| GSE19018 | Up | 0.4785794163 |
| GSE19899_A1 | Up | 0.0710749550 |
| GSE19899_A2 | Down | -0.5682519050 |
| PubMed_21979375_A1 | Down | -0.6670279081 |
| PubMed_21979375_A2 | Down | -0.2819723239 |
| GSE35957 | Down | -0.1841813524 |
| GSE36640 | Down | -0.1987910036 |
| GSE54402 | Down | -0.2176111632 |
| GSE9593 | Down | -0.1588324688 |
| GSE43922 | Up | 0.0064478549 |
| GSE24585 | Down | -0.0207151951 |
| GSE37065 | Down | -0.0949643943 |
| GSE28863_A1 | Up | 0.0134754854 |
| GSE28863_A2 | Down | -0.0491620429 |
| GSE28863_A3 | Up | 0.2091597007 |
| GSE28863_A4 | Up | 0.2652408260 |
| GSE48662 | Down | -0.0223872380 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017453 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT021941 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025641 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
