HCSGD entry for AK1
1. General information
| Official gene symbol | AK1 |
|---|---|
| Entrez ID | 203 |
| Gene full name | adenylate kinase 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001520 | Outer dense fiber | IEA | cellular_component |
| GO:0004017 | Adenylate kinase activity | IEA | molecular_function |
| GO:0004550 | Nucleoside diphosphate kinase activity | IDA IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006139 | Nucleobase-containing compound metabolic process | IEA | biological_process |
| GO:0006165 | Nucleoside diphosphate phosphorylation | IDA | biological_process |
| GO:0007050 | Cell cycle arrest | IEA | biological_process |
| GO:0009142 | Nucleoside triphosphate biosynthetic process | IDA IEA | biological_process |
| GO:0015949 | Nucleobase-containing small molecule interconversion | TAS | biological_process |
| GO:0019205 | Nucleobase-containing compound kinase activity | IEA | molecular_function |
| GO:0036126 | Sperm flagellum | IEA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046034 | ATP metabolic process | IEA | biological_process |
| GO:0055086 | Nucleobase-containing small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0631744881 | 0.8682344478 | 0.5429963867 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5936937353 |
| GSE13712_SHEAR | Down | -0.6199748691 |
| GSE13712_STATIC | Up | 0.0763783576 |
| GSE19018 | Up | 0.0924413125 |
| GSE19899_A1 | Up | 0.0728691774 |
| GSE19899_A2 | Up | 0.8856351919 |
| PubMed_21979375_A1 | Up | 0.2035335235 |
| PubMed_21979375_A2 | Up | 0.3733393254 |
| GSE35957 | Down | -0.3469037387 |
| GSE36640 | Up | 1.0811081418 |
| GSE54402 | Up | 0.0695959023 |
| GSE9593 | Down | -0.1178864971 |
| GSE43922 | Down | -0.0961172054 |
| GSE24585 | Up | 0.1954431807 |
| GSE37065 | Down | -0.0149769855 |
| GSE28863_A1 | Up | 0.0414826958 |
| GSE28863_A2 | Up | 0.1357085333 |
| GSE28863_A3 | Up | 0.0573313385 |
| GSE28863_A4 | Up | 0.1087687587 |
| GSE48662 | Up | 0.2203827041 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Bis(Adenosine)-5'-Pentaphosphate | DB01717 | EXPT00535 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-769-5p | MIMAT0003886 | MIRT039155 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT051000 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
