HCSGD entry for ENPEP
1. General information
Official gene symbol | ENPEP |
---|---|
Entrez ID | 2028 |
Gene full name | glutamyl aminopeptidase (aminopeptidase A) |
Other gene symbols | APA CD249 gp160 |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0001525 | Angiogenesis | ISS | biological_process |
GO:0002003 | Angiotensin maturation | TAS | biological_process |
GO:0002005 | Angiotensin catabolic process in blood | NAS | biological_process |
GO:0003081 | Regulation of systemic arterial blood pressure by renin-angiotensin | IDA NAS | biological_process |
GO:0004177 | Aminopeptidase activity | IDA | molecular_function |
GO:0005765 | Lysosomal membrane | IDA | cellular_component |
GO:0005886 | Plasma membrane | TAS | cellular_component |
GO:0005887 | Integral component of plasma membrane | NAS | cellular_component |
GO:0005903 | Brush border | ISS | cellular_component |
GO:0006508 | Proteolysis | IEA | biological_process |
GO:0007267 | Cell-cell signaling | NAS | biological_process |
GO:0008237 | Metallopeptidase activity | EXP | molecular_function |
GO:0008270 | Zinc ion binding | IEA | molecular_function |
GO:0008283 | Cell proliferation | IDA NAS | biological_process |
GO:0009897 | External side of plasma membrane | ISS | cellular_component |
GO:0016324 | Apical plasma membrane | ISS | cellular_component |
GO:0016477 | Cell migration | IDA | biological_process |
GO:0031410 | Cytoplasmic vesicle | ISS | cellular_component |
GO:0032835 | Glomerulus development | ISS | biological_process |
GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
GO:0045177 | Apical part of cell | ISS | cellular_component |
GO:0070006 | Metalloaminopeptidase activity | IDA NAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.8318336157 | 0.0997778200 | 0.9999902473 | 0.6044308400 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Down | -0.5572363140 |
GSE13712_SHEAR | Down | -0.0556608023 |
GSE13712_STATIC | Down | -0.0940640487 |
GSE19018 | Up | 0.2438712197 |
GSE19899_A1 | Up | 0.1002172274 |
GSE19899_A2 | Up | 0.2961256659 |
PubMed_21979375_A1 | Up | 0.1320506815 |
PubMed_21979375_A2 | Up | 0.2246194806 |
GSE35957 | Down | -0.1232783139 |
GSE36640 | Down | -1.3212199508 |
GSE54402 | Down | -0.0110765721 |
GSE9593 | Down | -0.5457484851 |
GSE43922 | Up | 0.0169578752 |
GSE24585 | Down | -0.7896987370 |
GSE37065 | Down | -0.0998239643 |
GSE28863_A1 | Down | -0.0166307605 |
GSE28863_A2 | Up | 0.0165487479 |
GSE28863_A3 | Up | 0.1075631315 |
GSE28863_A4 | Down | -0.0792594960 |
GSE48662 | Up | 0.0287319617 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
---|---|---|
L-Glutamic Acid | DB00142 | NUTR00027 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-320a | MIMAT0000510 | MIRT044621 | CLASH | Functional MTI (Weak) | 23622248 |
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