HCSGD entry for ENPEP


1. General information

Official gene symbolENPEP
Entrez ID2028
Gene full nameglutamyl aminopeptidase (aminopeptidase A)
Other gene symbolsAPA CD249 gp160
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisISSbiological_process
GO:0002003Angiotensin maturationTASbiological_process
GO:0002005Angiotensin catabolic process in bloodNASbiological_process
GO:0003081Regulation of systemic arterial blood pressure by renin-angiotensinIDA NASbiological_process
GO:0004177Aminopeptidase activityIDAmolecular_function
GO:0005765Lysosomal membraneIDAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneNAScellular_component
GO:0005903Brush borderISScellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0007267Cell-cell signalingNASbiological_process
GO:0008237Metallopeptidase activityEXPmolecular_function
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008283Cell proliferationIDA NASbiological_process
GO:0009897External side of plasma membraneISScellular_component
GO:0016324Apical plasma membraneISScellular_component
GO:0016477Cell migrationIDAbiological_process
GO:0031410Cytoplasmic vesicleISScellular_component
GO:0032835Glomerulus developmentISSbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0045177Apical part of cellISScellular_component
GO:0070006Metalloaminopeptidase activityIDA NASmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.83183361570.09977782000.99999024730.6044308400

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5572363140
GSE13712_SHEARDown-0.0556608023
GSE13712_STATICDown-0.0940640487
GSE19018Up0.2438712197
GSE19899_A1Up0.1002172274
GSE19899_A2Up0.2961256659
PubMed_21979375_A1Up0.1320506815
PubMed_21979375_A2Up0.2246194806
GSE35957Down-0.1232783139
GSE36640Down-1.3212199508
GSE54402Down-0.0110765721
GSE9593Down-0.5457484851
GSE43922Up0.0169578752
GSE24585Down-0.7896987370
GSE37065Down-0.0998239643
GSE28863_A1Down-0.0166307605
GSE28863_A2Up0.0165487479
GSE28863_A3Up0.1075631315
GSE28863_A4Down-0.0792594960
GSE48662Up0.0287319617

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Glutamic AcidDB00142 NUTR00027

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-320aMIMAT0000510MIRT044621CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.