HCSGD entry for ENO2
1. General information
| Official gene symbol | ENO2 |
|---|---|
| Entrez ID | 2026 |
| Gene full name | enolase 2 (gamma, neuronal) |
| Other gene symbols | NSE |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000015 | Phosphopyruvate hydratase complex | IEA | cellular_component |
| GO:0000287 | Magnesium ion binding | IEA | molecular_function |
| GO:0001917 | Photoreceptor inner segment | IEA | cellular_component |
| GO:0004634 | Phosphopyruvate hydratase activity | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006006 | Glucose metabolic process | TAS | biological_process |
| GO:0006094 | Gluconeogenesis | TAS | biological_process |
| GO:0006096 | Glycolysis | IEA TAS | biological_process |
| GO:0043204 | Perikaryon | IEA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0056709282 | 0.0451054899 | 0.1985117647 | 0.3991464046 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.8244843207 |
| GSE13712_SHEAR | Down | -1.0028972722 |
| GSE13712_STATIC | Down | -0.6922451027 |
| GSE19018 | Up | 3.3761688933 |
| GSE19899_A1 | Up | 0.6199393337 |
| GSE19899_A2 | Up | 0.2675689749 |
| PubMed_21979375_A1 | Down | -0.3343022122 |
| PubMed_21979375_A2 | Up | 0.7040602484 |
| GSE35957 | Down | -2.3194975362 |
| GSE36640 | Down | -0.8827987984 |
| GSE54402 | Up | 0.5796368763 |
| GSE9593 | Up | 0.3144603778 |
| GSE43922 | Up | 0.2420422582 |
| GSE24585 | Up | 0.4588410060 |
| GSE37065 | Up | 0.5717508735 |
| GSE28863_A1 | Down | -0.1256959037 |
| GSE28863_A2 | Up | 1.4819900382 |
| GSE28863_A3 | Down | -0.5261065076 |
| GSE28863_A4 | Down | -0.1200212080 |
| GSE48662 | Up | 0.4169934890 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 2-Phosphoglycolic Acid | DB02726 | EXPT02567 | DB02389 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-93-3p | MIMAT0004509 | MIRT038722 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99b-5p | MIMAT0000689 | MIRT044208 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
