HCSGD entry for ELK4
1. General information
| Official gene symbol | ELK4 |
|---|---|
| Entrez ID | 2005 |
| Gene full name | ELK4, ETS-domain protein (SRF accessory protein 1) |
| Other gene symbols | SAP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IMP | biological_process |
| GO:0001047 | Core promoter binding | TAS | molecular_function |
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0003682 | Chromatin binding | IDA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0003712 | Transcription cofactor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0070932 | Histone H3 deacetylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7369810494 | 0.4510354318 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1674163505 |
| GSE13712_SHEAR | Down | -0.1548925856 |
| GSE13712_STATIC | Down | -0.2926575685 |
| GSE19018 | Down | -0.2601211884 |
| GSE19899_A1 | Down | -0.0115650598 |
| GSE19899_A2 | Up | 0.0496990572 |
| PubMed_21979375_A1 | Down | -0.0059448741 |
| PubMed_21979375_A2 | Up | 0.0190499957 |
| GSE35957 | Up | 0.0745071230 |
| GSE36640 | Down | -0.2799478456 |
| GSE54402 | Up | 0.1112741373 |
| GSE9593 | Down | -0.0034856478 |
| GSE43922 | Up | 0.0438603590 |
| GSE24585 | Down | -0.1244619316 |
| GSE37065 | Down | -0.0058038915 |
| GSE28863_A1 | Up | 0.3715290955 |
| GSE28863_A2 | Up | 0.4627778230 |
| GSE28863_A3 | Down | -0.0952791702 |
| GSE28863_A4 | Down | -0.2586555551 |
| GSE48662 | Up | 0.5235344525 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT041755 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052289 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
