HCSGD entry for DAND5
1. General information
| Official gene symbol | DAND5 |
|---|---|
| Entrez ID | 199699 |
| Gene full name | DAN domain family member 5, BMP antagonist |
| Other gene symbols | CER2 CERL2 CKTSF1B3 COCO CRL2 DANTE GREM3 SP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003140 | Determination of left/right asymmetry in lateral mesoderm | ISS | biological_process |
| GO:0003281 | Ventricular septum development | ISS | biological_process |
| GO:0003283 | Atrial septum development | ISS | biological_process |
| GO:0005576 | Extracellular region | NAS | cellular_component |
| GO:0016015 | Morphogen activity | ISS | molecular_function |
| GO:0030512 | Negative regulation of transforming growth factor beta receptor signaling pathway | ISS | biological_process |
| GO:0030514 | Negative regulation of BMP signaling pathway | ISS | biological_process |
| GO:0038101 | Sequestering of nodal from receptor via nodal binding | ISS | biological_process |
| GO:0061371 | Determination of heart left/right asymmetry | ISS | biological_process |
| GO:1900108 | Negative regulation of nodal signaling pathway | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2212588503 | 0.8496688272 | 0.9026964817 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1087864683 |
| GSE13712_SHEAR | Down | -0.0597408807 |
| GSE13712_STATIC | Down | -0.3178084806 |
| GSE19018 | Up | 0.0595539819 |
| GSE19899_A1 | Up | 0.3143373560 |
| GSE19899_A2 | Up | 0.1892861362 |
| PubMed_21979375_A1 | Up | 0.1923440460 |
| PubMed_21979375_A2 | Down | -0.0194484647 |
| GSE35957 | Up | 0.0466423752 |
| GSE36640 | Up | 0.0625942661 |
| GSE54402 | Up | 0.1033100172 |
| GSE9593 | Down | -0.0427409531 |
| GSE43922 | Up | 0.3215961821 |
| GSE24585 | Down | -0.0711586998 |
| GSE37065 | Down | -0.1693669166 |
| GSE28863_A1 | Down | -0.0165054701 |
| GSE28863_A2 | Up | 0.2744251049 |
| GSE28863_A3 | Up | 0.2996281990 |
| GSE28863_A4 | Up | 0.2016270734 |
| GSE48662 | Down | -0.1404253363 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-29b-3p | MIMAT0000100 | NA | hsa-miR-29b | 19211935 | |||
| hsa-miR-218-5p | MIMAT0000275 | NA | hsa-miR-218 | {Western blot} | {overexpression by miRNA precursor transfection} | 19913496 | |
| hsa-miR-29b-3p | MIMAT0000100 | NA | hsa-miR-29b | {Western blot} | {overexpression by miRNA precursor transfection} | 19913496 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
