HCSGD entry for EIF4EBP2
1. General information
| Official gene symbol | EIF4EBP2 |
|---|---|
| Entrez ID | 1979 |
| Gene full name | eukaryotic translation initiation factor 4E binding protein 2 |
| Other gene symbols | 4EBP2 PHASII |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0008190 | Eukaryotic initiation factor 4E binding | IEA | molecular_function |
| GO:0008286 | Insulin receptor signaling pathway | IEA | biological_process |
| GO:0019933 | CAMP-mediated signaling | IEA | biological_process |
| GO:0045947 | Negative regulation of translational initiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0738911022 | 0.9255941644 | 0.5774607185 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1178864526 |
| GSE13712_SHEAR | Down | -0.1996441562 |
| GSE13712_STATIC | Down | -0.3537172798 |
| GSE19018 | Down | -0.2212210796 |
| GSE19899_A1 | Up | 0.0910386048 |
| GSE19899_A2 | Up | 0.2986523742 |
| PubMed_21979375_A1 | Up | 0.4286920236 |
| PubMed_21979375_A2 | Up | 0.4891739097 |
| GSE35957 | Up | 0.4470011142 |
| GSE36640 | Up | 0.5909163400 |
| GSE54402 | Up | 0.3124834804 |
| GSE9593 | Up | 0.1966501469 |
| GSE43922 | Up | 0.3149231866 |
| GSE24585 | Up | 0.4594986513 |
| GSE37065 | Down | -0.1143307213 |
| GSE28863_A1 | Down | -0.0581413996 |
| GSE28863_A2 | Up | 0.1250626427 |
| GSE28863_A3 | Down | -0.3332003668 |
| GSE28863_A4 | Up | 0.0450612297 |
| GSE48662 | Up | 0.2456682093 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019719 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025698 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030777 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-760 | MIMAT0004957 | MIRT036785 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036867 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-5p | MIMAT0000072 | MIRT050703 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051622 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
