HCSGD entry for EME2
1. General information
| Official gene symbol | EME2 |
|---|---|
| Entrez ID | 197342 |
| Gene full name | essential meiotic endonuclease 1 homolog 2 (S. pombe) |
| Other gene symbols | SLX2B gs125 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0004518 | Nuclease activity | IEA | molecular_function |
| GO:0004519 | Endonuclease activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0006310 | DNA recombination | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0128285779 | 0.9632433798 | 0.2830914501 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2202587081 |
| GSE13712_SHEAR | Up | 0.2930904553 |
| GSE13712_STATIC | Up | 0.2628442583 |
| GSE19018 | Down | -0.7864045546 |
| GSE19899_A1 | Up | 0.2617618477 |
| GSE19899_A2 | Up | 1.1615606703 |
| PubMed_21979375_A1 | Up | 1.4983494957 |
| PubMed_21979375_A2 | Up | 1.6700650169 |
| GSE35957 | Up | 0.1044244932 |
| GSE36640 | Up | 1.3679897454 |
| GSE54402 | Up | 0.5169095676 |
| GSE9593 | Up | 0.2054639950 |
| GSE43922 | Up | 0.1594803967 |
| GSE24585 | Down | -0.0418524405 |
| GSE37065 | Down | -0.1770449859 |
| GSE28863_A1 | Up | 0.0326056120 |
| GSE28863_A2 | Down | -0.0886254754 |
| GSE28863_A3 | Up | 0.2863206365 |
| GSE28863_A4 | Up | 0.0826798198 |
| GSE48662 | Up | 0.0594252567 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-25-3p | MIMAT0000081 | MIRT050291 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
