HCSGD entry for EHHADH
1. General information
| Official gene symbol | EHHADH |
|---|---|
| Entrez ID | 1962 |
| Gene full name | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| Other gene symbols | ECHD L-PBE LBFP LBP PBFE |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity | NAS | molecular_function |
| GO:0004165 | Dodecenoyl-CoA delta-isomerase activity | IEA | molecular_function |
| GO:0004300 | Enoyl-CoA hydratase activity | NAS | molecular_function |
| GO:0005102 | Receptor binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005777 | Peroxisome | IDA NAS | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0006475 | Internal protein amino acid acetylation | IDA | biological_process |
| GO:0006635 | Fatty acid beta-oxidation | IEA NAS | biological_process |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0050662 | Coenzyme binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8969534174 | 0.0011762205 | 0.9999902473 | 0.0649337526 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5851011669 |
| GSE13712_SHEAR | Up | 0.3147331368 |
| GSE13712_STATIC | Up | 0.7392457979 |
| GSE19018 | Up | 0.4334160590 |
| GSE19899_A1 | Down | -0.4690009742 |
| GSE19899_A2 | Down | -1.9125188801 |
| PubMed_21979375_A1 | Down | -2.6183811546 |
| PubMed_21979375_A2 | Down | -1.5798118268 |
| GSE35957 | Up | 0.2124734462 |
| GSE36640 | Down | -0.6845077346 |
| GSE54402 | Down | -1.8209543640 |
| GSE9593 | Down | -0.5285651926 |
| GSE43922 | Down | -1.1897531630 |
| GSE24585 | Up | 0.4689983264 |
| GSE37065 | Up | 0.1089149372 |
| GSE28863_A1 | Down | -0.5801385611 |
| GSE28863_A2 | Down | -0.3086314241 |
| GSE28863_A3 | Down | -0.6776852879 |
| GSE28863_A4 | Down | -0.2517994535 |
| GSE48662 | Down | -0.0851195247 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1226-3p | MIMAT0005577 | MIRT036469 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
