HCSGD entry for MEGF8
1. General information
| Official gene symbol | MEGF8 |
|---|---|
| Entrez ID | 1954 |
| Gene full name | multiple EGF-like-domains 8 |
| Other gene symbols | C19orf49 CRPT2 EGFL4 SBP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004872 | Receptor activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0061371 | Determination of heart left/right asymmetry | IEA | biological_process |
| GO:0071907 | Determination of digestive tract left/right asymmetry | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6012281220 | 0.0274977053 | 0.9999902473 | 0.3156787271 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2038013810 |
| GSE13712_SHEAR | Down | -0.5248000957 |
| GSE13712_STATIC | Down | -0.5476175618 |
| GSE19018 | Down | -0.0271136586 |
| GSE19899_A1 | Down | -0.2296391517 |
| GSE19899_A2 | Down | -0.7357951347 |
| PubMed_21979375_A1 | Down | -2.4110378371 |
| PubMed_21979375_A2 | Down | -0.0188458662 |
| GSE35957 | Down | -0.3471775608 |
| GSE36640 | Down | -0.8006661379 |
| GSE54402 | Down | -0.3390324613 |
| GSE9593 | Up | 0.0477586220 |
| GSE43922 | Up | 0.0472982541 |
| GSE24585 | Down | -0.1186514768 |
| GSE37065 | Down | -0.1628308320 |
| GSE28863_A1 | Up | 0.7261236231 |
| GSE28863_A2 | Up | 0.5759086343 |
| GSE28863_A3 | Up | 0.3269236337 |
| GSE28863_A4 | Down | -0.1392625269 |
| GSE48662 | Up | 0.5866114305 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029661 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040080 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041496 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042296 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051194 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
