HCSGD entry for CELSR3
1. General information
| Official gene symbol | CELSR3 |
|---|---|
| Entrez ID | 1951 |
| Gene full name | cadherin, EGF LAG seven-pass G-type receptor 3 |
| Other gene symbols | CDHF11 EGFL1 FMI1 HFMI1 MEGF2 RESDA1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001764 | Neuron migration | IEA | biological_process |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007156 | Homophilic cell adhesion | IEA | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007218 | Neuropeptide signaling pathway | IEA | biological_process |
| GO:0007413 | Axonal fasciculation | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0032880 | Regulation of protein localization | IEA | biological_process |
| GO:0042384 | Cilium assembly | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7056444056 | 0.6157135747 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0048041780 |
| GSE13712_SHEAR | Up | 0.1343160484 |
| GSE13712_STATIC | Down | -0.1539102350 |
| GSE19018 | Down | -0.2191562304 |
| GSE19899_A1 | Down | -0.0890704865 |
| GSE19899_A2 | Down | -0.0904093542 |
| PubMed_21979375_A1 | Up | 0.2529258636 |
| PubMed_21979375_A2 | Up | 0.1330402674 |
| GSE35957 | Down | -0.2135267116 |
| GSE36640 | Up | 0.1838727703 |
| GSE54402 | Down | -0.3748650181 |
| GSE9593 | Up | 0.2219372461 |
| GSE43922 | Up | 0.0709545318 |
| GSE24585 | Up | 0.0403491234 |
| GSE37065 | Up | 0.0778581281 |
| GSE28863_A1 | Down | -0.0723713888 |
| GSE28863_A2 | Up | 0.2477110831 |
| GSE28863_A3 | Up | 0.0001944601 |
| GSE28863_A4 | Down | -0.1051246317 |
| GSE48662 | Up | 0.0584426311 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017431 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT048022 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26149270 | This feature incudes (a) Nestin, involved in stem cell recruitment and glial cell activation; (b) A Kinase anchor protein, released as consequence of mitochondrial damage and Rho activation establishing cell shape and motility; (c) Actin related protein 2/3 complex, involved in actin polymerization and cell shape maintenance |
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