HCSGD entry for EFNA5

1. General information

Official gene symbolEFNA5
Entrez ID1946
Gene full nameephrin-A5
Other gene symbolsAF1 EFL5 EPLG7 GLC1M LERK7 RAGS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005886Plasma membraneISScellular_component
GO:0005901CaveolaIEAcellular_component
GO:0006915Apoptotic processIDAbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0016020MembraneIEAcellular_component
GO:0022407Regulation of cell-cell adhesionIDAbiological_process
GO:0031290Retinal ganglion cell axon guidanceIEAbiological_process
GO:0031362Anchored component of external side of plasma membraneIDAcellular_component
GO:0032314Regulation of Rac GTPase activityISSbiological_process
GO:0032319Regulation of Rho GTPase activityIDAbiological_process
GO:0032956Regulation of actin cytoskeleton organizationIDAbiological_process
GO:0045499Chemorepellent activityIEAmolecular_function
GO:0046875Ephrin receptor bindingIPImolecular_function
GO:0048013Ephrin receptor signaling pathwayIDAbiological_process
GO:0050731Positive regulation of peptidyl-tyrosine phosphorylationISSbiological_process
GO:0051893Regulation of focal adhesion assemblyIDAbiological_process
GO:0061178Regulation of insulin secretion involved in cellular response to glucose stimulusISSbiological_process
GO:0070507Regulation of microtubule cytoskeleton organizationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07240355610.12978429390.57319146120.6934738936

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.6280060325
GSE13712_SHEARDown-0.1495702940
GSE13712_STATICDown-0.1595742168
GSE19018Down-0.4297213715
GSE19899_A1Down-0.1187412793
GSE19899_A2Up0.1372920890
PubMed_21979375_A1Down-0.3397506847
PubMed_21979375_A2Up0.9926734819
GSE35957Down-1.4308263288
GSE36640Up0.2484533678
GSE54402Down-0.4957410281
GSE9593Down-0.1310298835
GSE43922Up0.0230987796
GSE24585Down-0.4271905515
GSE37065Down-0.4252085885
GSE28863_A1Up1.0256174989
GSE28863_A2Up1.3783159434
GSE28863_A3Up0.3826981930
GSE28863_A4Down-0.1110830454
GSE48662Up0.2592356095

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018356MicroarrayFunctional MTI (Weak)18185580
hsa-miR-92a-3pMIMAT0000092MIRT049051CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.