HCSGD entry for EEF1D
1. General information
| Official gene symbol | EEF1D |
|---|---|
| Entrez ID | 1936 |
| Gene full name | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| Other gene symbols | EF-1D EF1D FP1047 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003746 | Translation elongation factor activity | IEA | molecular_function |
| GO:0004871 | Signal transducer activity | IMP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005853 | Eukaryotic translation elongation factor 1 complex | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006414 | Translational elongation | TAS | biological_process |
| GO:0007165 | Signal transduction | IMP | biological_process |
| GO:0008135 | Translation factor activity, nucleic acid binding | TAS | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB signaling | IMP | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9311418335 | 0.1138630333 | 0.9999902473 | 0.6468786747 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0177204453 |
| GSE13712_SHEAR | Down | -0.2002444688 |
| GSE13712_STATIC | Down | -0.2228653030 |
| GSE19018 | Up | 0.0974053730 |
| GSE19899_A1 | Down | -0.0674491832 |
| GSE19899_A2 | Down | -0.0128828456 |
| PubMed_21979375_A1 | Down | -0.0236604204 |
| PubMed_21979375_A2 | Down | -0.5437824223 |
| GSE35957 | Up | 0.0227689533 |
| GSE36640 | Down | -0.4036092623 |
| GSE54402 | Up | 0.1896003793 |
| GSE9593 | Down | -0.1903829093 |
| GSE43922 | Down | -0.0224600247 |
| GSE24585 | Down | -0.1011226924 |
| GSE37065 | Down | -0.1677689545 |
| GSE28863_A1 | Down | -0.2274534234 |
| GSE28863_A2 | Down | -0.1704883005 |
| GSE28863_A3 | Up | 0.3040047120 |
| GSE28863_A4 | Down | -0.0470954510 |
| GSE48662 | Down | -0.1510094656 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-93-3p | MIMAT0004509 | MIRT038906 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT044945 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045464 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
