HCSGD entry for PHC1
1. General information
| Official gene symbol | PHC1 |
|---|---|
| Entrez ID | 1911 |
| Gene full name | polyhomeotic homolog 1 (Drosophila) |
| Other gene symbols | EDR1 HPH1 RAE28 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001739 | Sex chromatin | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016574 | Histone ubiquitination | IDA | biological_process |
| GO:0016604 | Nuclear body | IEA | cellular_component |
| GO:0031519 | PcG protein complex | IDA | cellular_component |
| GO:0035102 | PRC1 complex | IDA | cellular_component |
| GO:0071300 | Cellular response to retinoic acid | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9960219786 | 0.0038049998 | 0.9999902473 | 0.1255030075 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1729698503 |
| GSE13712_SHEAR | Down | -0.9556807841 |
| GSE13712_STATIC | Down | -0.8114042675 |
| GSE19018 | Down | -0.4963870353 |
| GSE19899_A1 | Down | -0.2264056130 |
| GSE19899_A2 | Down | -0.5977075667 |
| PubMed_21979375_A1 | Down | -0.2234487725 |
| PubMed_21979375_A2 | Down | -0.0873566963 |
| GSE35957 | Down | -0.7059747077 |
| GSE36640 | Down | -0.5498204654 |
| GSE54402 | Up | 0.0084427706 |
| GSE9593 | Down | -0.5524507501 |
| GSE43922 | Down | -0.3633583263 |
| GSE24585 | Up | 0.3953499337 |
| GSE37065 | Down | -0.1423353295 |
| GSE28863_A1 | Down | -0.2078893749 |
| GSE28863_A2 | Down | -1.1200542500 |
| GSE28863_A3 | Down | -0.1572473421 |
| GSE28863_A4 | Down | -0.0226479010 |
| GSE48662 | Down | -0.2676974618 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036290 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050613 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
