HCSGD entry for ECH1
1. General information
| Official gene symbol | ECH1 |
|---|---|
| Entrez ID | 1891 |
| Gene full name | enoyl CoA hydratase 1, peroxisomal |
| Other gene symbols | HPXEL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0005102 | Receptor binding | IPI | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IDA IEA | cellular_component |
| GO:0005777 | Peroxisome | NAS | cellular_component |
| GO:0006635 | Fatty acid beta-oxidation | IEA | biological_process |
| GO:0016853 | Isomerase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6330645530 | 0.1518921887 | 0.9999902473 | 0.7523436771 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1280114315 |
| GSE13712_SHEAR | Down | -0.3535159937 |
| GSE13712_STATIC | Down | -0.2306428282 |
| GSE19018 | Down | -0.2273559947 |
| GSE19899_A1 | Down | -0.3655575137 |
| GSE19899_A2 | Down | -0.5405157297 |
| PubMed_21979375_A1 | Up | 0.3183981716 |
| PubMed_21979375_A2 | Up | 0.1115993266 |
| GSE35957 | Down | -0.1341761880 |
| GSE36640 | Up | 0.5278362702 |
| GSE54402 | Down | -0.4765903579 |
| GSE9593 | Up | 0.0136021154 |
| GSE43922 | Down | -0.7556161014 |
| GSE24585 | Up | 0.4839674759 |
| GSE37065 | Up | 0.2157688851 |
| GSE28863_A1 | Up | 0.0539735027 |
| GSE28863_A2 | Up | 0.0110640656 |
| GSE28863_A3 | Up | 0.0059414841 |
| GSE28863_A4 | Up | 0.0639032743 |
| GSE48662 | Up | 0.2802239431 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016583 | Proteomics | Functional MTI (Weak) | 21512034 |
| hsa-miR-340-5p | MIMAT0004692 | MIRT019571 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029968 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043922 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044420 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045040 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046350 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
