HCSGD entry for GPR183
1. General information
| Official gene symbol | GPR183 |
|---|---|
| Entrez ID | 1880 |
| Gene full name | G protein-coupled receptor 183 |
| Other gene symbols | EBI2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002313 | Mature B cell differentiation involved in immune response | ISS | biological_process |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006955 | Immune response | TAS | biological_process |
| GO:0006959 | Humoral immune response | ISS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | IDA | biological_process |
| GO:0008142 | Oxysterol binding | IDA | molecular_function |
| GO:0030890 | Positive regulation of B cell proliferation | IDA | biological_process |
| GO:0070374 | Positive regulation of ERK1 and ERK2 cascade | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0269322746 | 0.2852996201 | 0.3820504567 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1749332453 |
| GSE13712_SHEAR | Down | -0.1556427143 |
| GSE13712_STATIC | Up | 0.1342345665 |
| GSE19018 | Down | -0.1950899404 |
| GSE19899_A1 | Up | 0.1775254931 |
| GSE19899_A2 | Up | 0.9554438744 |
| PubMed_21979375_A1 | Up | 2.8830696054 |
| PubMed_21979375_A2 | Up | 2.3748802699 |
| GSE35957 | Up | 0.0536473904 |
| GSE36640 | Down | -0.2867429362 |
| GSE54402 | Up | 0.2445521605 |
| GSE9593 | Down | -0.5166605264 |
| GSE43922 | Up | 0.9456404403 |
| GSE24585 | Up | 0.0441547861 |
| GSE37065 | Down | -0.0752149282 |
| GSE28863_A1 | Down | -0.5033303013 |
| GSE28863_A2 | Down | -0.6688065520 |
| GSE28863_A3 | Up | 0.1297061721 |
| GSE28863_A4 | Down | -0.0817345970 |
| GSE48662 | Up | 0.1423936793 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029809 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
