HCSGD entry for E4F1
1. General information
| Official gene symbol | E4F1 |
|---|---|
| Entrez ID | 1877 |
| Gene full name | E4F transcription factor 1 |
| Other gene symbols | E4F |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | TAS | molecular_function |
| GO:0003713 | Transcription coactivator activity | TAS | molecular_function |
| GO:0003714 | Transcription corepressor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005819 | Spindle | IEA | cellular_component |
| GO:0006260 | DNA replication | IEA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0009790 | Embryo development | IEA | biological_process |
| GO:0009794 | Regulation of mitotic cell cycle, embryonic | IEA | biological_process |
| GO:0010564 | Regulation of cell cycle process | IDA | biological_process |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0035497 | CAMP response element binding | IDA | molecular_function |
| GO:0040008 | Regulation of growth | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0071850 | Mitotic cell cycle arrest | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0546039816 | 0.9433767448 | 0.5102611072 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2114403288 |
| GSE13712_SHEAR | Up | 0.0938367837 |
| GSE13712_STATIC | Up | 0.3294664675 |
| GSE19018 | Up | 0.1193875427 |
| GSE19899_A1 | Up | 0.0284097385 |
| GSE19899_A2 | Up | 0.5811116419 |
| PubMed_21979375_A1 | Up | 0.8410187464 |
| PubMed_21979375_A2 | Up | 1.3487390617 |
| GSE35957 | Down | -0.2519389942 |
| GSE36640 | Up | 0.4384912778 |
| GSE54402 | Up | 0.1573898521 |
| GSE9593 | Down | -0.0223359139 |
| GSE43922 | Up | 0.0545392555 |
| GSE24585 | Down | -0.2006606928 |
| GSE37065 | Down | -0.1927627541 |
| GSE28863_A1 | Up | 0.0967865776 |
| GSE28863_A2 | Up | 0.4882132034 |
| GSE28863_A3 | Up | 0.2424617650 |
| GSE28863_A4 | Down | -0.1231162070 |
| GSE48662 | Up | 0.0264561794 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048699 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049823 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
