HCSGD entry for TOR1A
1. General information
| Official gene symbol | TOR1A |
|---|---|
| Entrez ID | 1861 |
| Gene full name | torsin family 1, member A (torsin A) |
| Other gene symbols | DQ2 DYT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004252 | Serine-type endopeptidase activity | TAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | TAS | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | IDA | cellular_component |
| GO:0006457 | Protein folding | TAS | biological_process |
| GO:0006979 | Response to oxidative stress | IEA | biological_process |
| GO:0006986 | Response to unfolded protein | TAS | biological_process |
| GO:0019894 | Kinesin binding | IEA | molecular_function |
| GO:0030659 | Cytoplasmic vesicle membrane | IEA | cellular_component |
| GO:0031965 | Nuclear membrane | IEA | cellular_component |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0051082 | Unfolded protein binding | TAS | molecular_function |
| GO:0051085 | Chaperone mediated protein folding requiring cofactor | IEA | biological_process |
| GO:0051260 | Protein homooligomerization | IDA | biological_process |
| GO:0071763 | Nuclear membrane organization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1231059572 | 0.9502265491 | 0.7175092781 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3131082847 |
| GSE13712_SHEAR | Up | 0.1295336773 |
| GSE13712_STATIC | Down | -0.0663532833 |
| GSE19018 | Down | -0.2941983153 |
| GSE19899_A1 | Up | 0.0683286876 |
| GSE19899_A2 | Up | 0.3234826106 |
| PubMed_21979375_A1 | Up | 0.3535745712 |
| PubMed_21979375_A2 | Up | 0.1896383999 |
| GSE35957 | Up | 0.0263905886 |
| GSE36640 | Up | 0.5233340975 |
| GSE54402 | Up | 0.2514331622 |
| GSE9593 | Up | 0.0905418720 |
| GSE43922 | Up | 0.1173616860 |
| GSE24585 | Down | -0.1583835346 |
| GSE37065 | Up | 0.1001870249 |
| GSE28863_A1 | Down | -0.0687198280 |
| GSE28863_A2 | Up | 0.2490683291 |
| GSE28863_A3 | Down | -0.4603871371 |
| GSE28863_A4 | Up | 0.2839786207 |
| GSE48662 | Up | 0.2192309964 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT051256 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
