HCSGD entry for DVL1

1. General information

Official gene symbolDVL1
Entrez ID1855
Gene full namedishevelled segment polarity protein 1
Other gene symbolsDVL DVL1L1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001505Regulation of neurotransmitter levelsISSbiological_process
GO:0004871Signal transducer activityIEAmolecular_function
GO:0005109Frizzled bindingIPImolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolIEAcellular_component
GO:0005874MicrotubuleIBAcellular_component
GO:0005938Cell cortexIBAcellular_component
GO:0006366Transcription from RNA polymerase II promoterIDAbiological_process
GO:0006469Negative regulation of protein kinase activityIDAbiological_process
GO:0007269Neurotransmitter secretionISSbiological_process
GO:0007411Axon guidanceIBAbiological_process
GO:0007528Neuromuscular junction developmentISSbiological_process
GO:0010976Positive regulation of neuron projection developmentIEAbiological_process
GO:0016023Cytoplasmic membrane-bounded vesicleISScellular_component
GO:0016328Lateral plasma membraneIDAcellular_component
GO:0019899Enzyme bindingIPImolecular_function
GO:0019901Protein kinase bindingIPImolecular_function
GO:0021915Neural tube developmentIEPbiological_process
GO:0022007Convergent extension involved in neural plate elongationIEAbiological_process
GO:0030136Clathrin-coated vesicleIBAcellular_component
GO:0030177Positive regulation of Wnt signaling pathwayIDAbiological_process
GO:0030424AxonIBAcellular_component
GO:0030425DendriteIBAcellular_component
GO:0030426Growth coneIBAcellular_component
GO:0031122Cytoplasmic microtubule organizationIEAbiological_process
GO:0031410Cytoplasmic vesicleIDAcellular_component
GO:0032091Negative regulation of protein bindingIDAbiological_process
GO:0032436Positive regulation of proteasomal ubiquitin-dependent protein catabolic processIMPbiological_process
GO:0034504Protein localization to nucleusIMPbiological_process
GO:0035176Social behaviorIEAbiological_process
GO:0035372Protein localization to microtubuleIEAbiological_process
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0042802Identical protein bindingIPImolecular_function
GO:0043025Neuronal cell bodyIBAcellular_component
GO:0043113Receptor clusteringISSbiological_process
GO:0045202SynapseIBA ISScellular_component
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0048365Rac GTPase bindingIBAmolecular_function
GO:0048668Collateral sproutingIBAbiological_process
GO:0048675Axon extensionIBAbiological_process
GO:0048813Dendrite morphogenesisIBA ISSbiological_process
GO:0050808Synapse organizationISSbiological_process
GO:0060026Convergent extensionIBAbiological_process
GO:0060070Canonical Wnt signaling pathwayIDAbiological_process
GO:0060071Wnt signaling pathway, planar cell polarity pathwayIDAbiological_process
GO:0060134Prepulse inhibitionIEAbiological_process
GO:0071340Skeletal muscle acetylcholine-gated channel clusteringIBAbiological_process
GO:0090103Cochlea morphogenesisIBAbiological_process
GO:0090179Planar cell polarity pathway involved in neural tube closureIBAbiological_process
GO:0090263Positive regulation of canonical Wnt signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.27545657460.72534327720.97143518541.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2136178329
GSE13712_SHEARUp0.2775733278
GSE13712_STATICDown-0.1717610624
GSE19018Up0.1010969722
GSE19899_A1Down-0.1513314467
GSE19899_A2Up0.1832764452
PubMed_21979375_A1Up0.2452775373
PubMed_21979375_A2Down-0.1010364508
GSE35957Down-0.2095098232
GSE36640Up0.2987337443
GSE54402Up0.2253452228
GSE9593Down-0.0733916438
GSE43922Up0.0575508371
GSE24585Down-0.3565682127
GSE37065Down-0.0150357923
GSE28863_A1Down-0.1789846024
GSE28863_A2Up0.0791390964
GSE28863_A3Up0.2868912052
GSE28863_A4Up0.1467024509
GSE48662Up0.2069523892

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-744-5pMIMAT0004945MIRT037606CLASHFunctional MTI (Weak)23622248
hsa-miR-378a-3pMIMAT0000732MIRT043927CLASHFunctional MTI (Weak)23622248
hsa-miR-10a-5pMIMAT0000253MIRT047691CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.