HCSGD entry for DUSP5


1. General information

Official gene symbolDUSP5
Entrez ID1847
Gene full namedual specificity phosphatase 5
Other gene symbolsDUSP HVH3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000188Inactivation of MAPK activityIBAbiological_process
GO:0001706Endoderm formationIBAbiological_process
GO:0004725Protein tyrosine phosphatase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005654NucleoplasmIBAcellular_component
GO:0006470Protein dephosphorylationIBAbiological_process
GO:0017017MAP kinase tyrosine/serine/threonine phosphatase activityIBAmolecular_function
GO:0035335Peptidyl-tyrosine dephosphorylationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00073798490.43495866800.07733166021.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.8695055284
GSE13712_SHEARDown-0.3664663418
GSE13712_STATICUp0.2798962519
GSE19018Up0.3728178166
GSE19899_A1Up2.4802943978
GSE19899_A2Up1.8525001702
PubMed_21979375_A1Up2.7898637589
PubMed_21979375_A2Up1.6959892672
GSE35957Down-0.8869632802
GSE36640Down-0.4979925979
GSE54402Up2.4751816808
GSE9593Up1.8802410187
GSE43922Up1.0195004249
GSE24585Down-0.2637201524
GSE37065Up0.4191938416
GSE28863_A1Down-0.3632665989
GSE28863_A2Up0.1095284614
GSE28863_A3Up0.1485958728
GSE28863_A4Up0.0282964801
GSE48662Down-0.0817747294

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-181a-5pMIMAT0000256MIRT006483Luciferase reporter assay//Western blotFunctional MTI17382377
hsa-miR-335-5pMIMAT0000765MIRT017083MicroarrayFunctional MTI (Weak)18185580
hsa-miR-27b-3pMIMAT0000419MIRT046191CLASHFunctional MTI (Weak)23622248
hsa-miR-27a-3pMIMAT0000084MIRT050016CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.