HCSGD entry for DSC2
1. General information
| Official gene symbol | DSC2 |
|---|---|
| Entrez ID | 1824 |
| Gene full name | desmocollin 2 |
| Other gene symbols | ARVD11 CDHF2 DG2 DGII/III DSC3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005913 | Cell-cell adherens junction | IEA | cellular_component |
| GO:0007155 | Cell adhesion | TAS | biological_process |
| GO:0007156 | Homophilic cell adhesion | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030057 | Desmosome | IDA | cellular_component |
| GO:0086005 | Ventricular cardiac muscle cell action potential | IMP | biological_process |
| GO:0086069 | Bundle of His cell to Purkinje myocyte communication | IMP | biological_process |
| GO:0086091 | Regulation of heart rate by cardiac conduction | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6969951028 | 0.8158605220 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0006994731 |
| GSE13712_SHEAR | Up | 0.1292160635 |
| GSE13712_STATIC | Down | -0.0260049902 |
| GSE19018 | Up | 0.0930364655 |
| GSE19899_A1 | Up | 0.0761272555 |
| GSE19899_A2 | Up | 0.0888235950 |
| PubMed_21979375_A1 | Down | -0.0758986310 |
| PubMed_21979375_A2 | Down | -0.1724294705 |
| GSE35957 | Up | 0.0702583309 |
| GSE36640 | Up | 0.0623554158 |
| GSE54402 | Up | 0.0793289710 |
| GSE9593 | Up | 0.0163604889 |
| GSE43922 | Up | 0.0115638150 |
| GSE24585 | Up | 0.0517252521 |
| GSE37065 | Up | 0.4522812085 |
| GSE28863_A1 | Down | -0.1450580100 |
| GSE28863_A2 | Down | -0.0323043766 |
| GSE28863_A3 | Up | 0.0368583768 |
| GSE28863_A4 | Up | 0.0725907356 |
| GSE48662 | Down | -0.0400078109 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019103 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025897 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030595 | Microarray | Functional MTI (Weak) | 19748357 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
