HCSGD entry for ATN1
1. General information
| Official gene symbol | ATN1 |
|---|---|
| Entrez ID | 1822 |
| Gene full name | atrophin 1 |
| Other gene symbols | B37 D12S755E DRPLA HRS NOD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0003714 | Transcription corepressor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007417 | Central nervous system development | TAS | biological_process |
| GO:0009404 | Toxin metabolic process | IEA | biological_process |
| GO:0016363 | Nuclear matrix | IDA | cellular_component |
| GO:0016477 | Cell migration | IEA | biological_process |
| GO:0019904 | Protein domain specific binding | IPI | molecular_function |
| GO:0030011 | Maintenance of cell polarity | IEA | biological_process |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0050827 | Toxin receptor binding | IEA | molecular_function |
| GO:0051402 | Neuron apoptotic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6863450933 | 0.4575003837 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0180878100 |
| GSE13712_SHEAR | Down | -0.0555609202 |
| GSE13712_STATIC | Down | -0.2087564170 |
| GSE19018 | Down | -0.0064248483 |
| GSE19899_A1 | Down | -0.0308250782 |
| GSE19899_A2 | Up | 0.1491568450 |
| PubMed_21979375_A1 | Up | 0.1682652760 |
| PubMed_21979375_A2 | Down | -0.1077263610 |
| GSE35957 | Up | 0.2066012356 |
| GSE36640 | Up | 0.1114220527 |
| GSE54402 | Down | -0.0784845795 |
| GSE9593 | Down | -0.1449041674 |
| GSE43922 | Down | -0.2371315146 |
| GSE24585 | Down | -0.0662879398 |
| GSE37065 | Down | -0.1659102333 |
| GSE28863_A1 | Up | 0.0390825600 |
| GSE28863_A2 | Up | 0.0692324673 |
| GSE28863_A3 | Up | 0.1858211583 |
| GSE28863_A4 | Down | -0.1195032279 |
| GSE48662 | Up | 0.4574467184 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-320b | MIMAT0005792 | MIRT036202 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-505-5p | MIMAT0004776 | MIRT037953 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038080 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-361-3p | MIMAT0004682 | MIRT038277 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040408 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042044 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045454 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-27b-3p | MIMAT0000419 | MIRT046183 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-27a-3p | MIMAT0000084 | MIRT050031 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050303 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
