HCSGD entry for DPYSL3

1. General information

Official gene symbolDPYSL3
Entrez ID1809
Gene full namedihydropyrimidinase-like 3
Other gene symbolsCRMP-4 CRMP4 DRP-3 DRP3 LCRMP ULIP ULIP-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005615Extracellular spaceIEA ISScellular_component
GO:0005829CytosolIEA ISS TAScellular_component
GO:0006208Pyrimidine nucleobase catabolic processIEAbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0010976Positive regulation of neuron projection developmentIEA ISSbiological_process
GO:0010977Negative regulation of neuron projection developmentIEA ISSbiological_process
GO:0016810Hydrolase activity, acting on carbon-nitrogen (but not peptide) bondsIEAmolecular_function
GO:0016812Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidesIEAmolecular_function
GO:0017124SH3 domain bindingIEA ISSmolecular_function
GO:0030027LamellipodiumIEA ISScellular_component
GO:0030336Negative regulation of cell migrationIEA ISSbiological_process
GO:0030426Growth coneIEA ISScellular_component
GO:0031941Filamentous actinIEA ISScellular_component
GO:0035374Chondroitin sulfate bindingIEA ISSmolecular_function
GO:0044297Cell bodyIEA ISScellular_component
GO:0048666Neuron developmentIEAbiological_process
GO:0048678Response to axon injuryIEA ISSbiological_process
GO:0051017Actin filament bundle assemblyIEA ISSbiological_process
GO:0051219Phosphoprotein bindingIEAmolecular_function
GO:0051260Protein homooligomerizationIEA ISSbiological_process
GO:0051491Positive regulation of filopodium assemblyIEA ISSbiological_process
GO:0051764Actin crosslink formationIEA ISSbiological_process
GO:0070382Exocytic vesicleISScellular_component
GO:0071345Cellular response to cytokine stimulusIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98435355420.00171978650.99999024730.0794414035

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1625709573
GSE13712_SHEARDown-0.9029583832
GSE13712_STATICDown-0.6138226731
GSE19018Down-0.3167415033
GSE19899_A1Down-0.5816482452
GSE19899_A2Down-1.5338344305
PubMed_21979375_A1Down-0.9908400811
PubMed_21979375_A2Down-1.5988564839
GSE35957Down-0.3335611303
GSE36640Down-1.3176767544
GSE54402Down-0.0565205643
GSE9593Down-0.7115243207
GSE43922Down-0.6666931137
GSE24585Down-0.0028379153
GSE37065Up0.0226249018
GSE28863_A1Up0.2942180999
GSE28863_A2Up0.7371455892
GSE28863_A3Down-1.0234174745
GSE28863_A4Down-0.0894173626
GSE48662Down-0.2478456052

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-197-3pMIMAT0000227MIRT004195MicroarrayFunctional MTI (Weak)16822819
hsa-miR-375MIMAT0000728MIRT020059MicroarrayFunctional MTI (Weak)20215506
hsa-miR-26b-5pMIMAT0000083MIRT030031MicroarrayFunctional MTI (Weak)19088304
hsa-miR-423-3pMIMAT0001340MIRT042483CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.