HCSGD entry for ABAT

1. General information

Official gene symbolABAT
Entrez ID18
Gene full name4-aminobutyrate aminotransferase
Other gene symbolsGABA-AT GABAT NPD009
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001666Response to hypoxiaIEAbiological_process
GO:00038674-aminobutyrate transaminase activityIDA IEA TASmolecular_function
GO:0005739MitochondrionIDA ISScellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0007268Synaptic transmissionTASbiological_process
GO:0007269Neurotransmitter secretionTASbiological_process
GO:0007610BehaviorNASbiological_process
GO:0007620CopulationIEAbiological_process
GO:0007626Locomotory behaviorIEAbiological_process
GO:0009448Gamma-aminobutyric acid metabolic processIEAbiological_process
GO:0009450Gamma-aminobutyric acid catabolic processNASbiological_process
GO:0010039Response to iron ionIEAbiological_process
GO:0030170Pyridoxal phosphate bindingIDA IEAmolecular_function
GO:00321444-aminobutyrate transaminase complexIDAcellular_component
GO:0032145Succinate-semialdehyde dehydrogenase bindingISSmolecular_function
GO:0035094Response to nicotineIEAbiological_process
GO:0042135Neurotransmitter catabolic processNASbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0043005Neuron projectionIEAcellular_component
GO:0045471Response to ethanolIEAbiological_process
GO:0045776Negative regulation of blood pressureIEAbiological_process
GO:0047298(S)-3-amino-2-methylpropionate transaminase activityIEAmolecular_function
GO:0048148Behavioral response to cocaineIEA ISSbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.36851501840.00890375750.99999024730.1869709729

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4130474498
GSE13712_SHEARDown-0.3679488951
GSE13712_STATICDown-0.9557745447
GSE19018Down-0.2935903732
GSE19899_A1Down-0.7441174883
GSE19899_A2Down-2.8262307560
PubMed_21979375_A1Down-1.0518582753
PubMed_21979375_A2Down-2.4416733050
GSE35957Up0.4029647082
GSE36640Up0.7642674858
GSE54402Up0.1628685274
GSE9593Up0.6249539147
GSE43922Down-1.2534824287
GSE24585Up0.3455625608
GSE37065Down-0.1151663083
GSE28863_A1Down-0.2344376477
GSE28863_A2Down-0.2828041528
GSE28863_A3Up0.5767924251
GSE28863_A4Down-0.1700669307
GSE48662Up0.2939047624

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Glutamic AcidDB00142 NUTR00027
L-AlanineDB00160 NUTR00013
PhenelzineDB00780 APRD00099
VigabatrinDB01080 APRD00282
(4e)-4-Aminohex-4-Enoic AcidDB01699 EXPT01579
4-Amino Hexanoic AcidDB04235 EXPT03223

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017324MicroarrayFunctional MTI (Weak)18185580
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.