HCSGD entry for DNTT
1. General information
| Official gene symbol | DNTT |
|---|---|
| Entrez ID | 1791 |
| Gene full name | DNA nucleotidylexotransferase |
| Other gene symbols | TDT |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003887 | DNA-directed DNA polymerase activity | IEA | molecular_function |
| GO:0003912 | DNA nucleotidylexotransferase activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006304 | DNA modification | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5345301584 | 0.9447649215 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0675106135 |
| GSE13712_SHEAR | Up | 0.0501992791 |
| GSE13712_STATIC | Down | -0.1956248424 |
| GSE19018 | Up | 0.0441559145 |
| GSE19899_A1 | Up | 0.0098450666 |
| GSE19899_A2 | Up | 0.1620789073 |
| PubMed_21979375_A1 | Up | 0.0524085276 |
| PubMed_21979375_A2 | Up | 0.1428744187 |
| GSE35957 | Up | 0.1262277355 |
| GSE36640 | Up | 0.1655032164 |
| GSE54402 | Up | 0.0757522569 |
| GSE9593 | Up | 0.0229369760 |
| GSE43922 | Up | 0.0381114772 |
| GSE24585 | Up | 0.1529737523 |
| GSE37065 | Down | -0.0240863440 |
| GSE28863_A1 | Down | -0.0064220922 |
| GSE28863_A2 | Down | -0.0447711191 |
| GSE28863_A3 | Up | 0.1309380834 |
| GSE28863_A4 | Up | 0.1148885516 |
| GSE48662 | Up | 0.0619615507 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 2',3'-Dideoxyadenosine-5'-Triphosphate | DB02189 | EXPT01104 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26084784 | Retaining terminal transferase activity of telomerase, the ribonucleoprotein enzyme which add telomeric repeats on chromosome end is thought to be required to prevent cellular ageing |
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