HCSGD entry for DYNC1I2
1. General information
| Official gene symbol | DYNC1I2 |
|---|---|
| Entrez ID | 1781 |
| Gene full name | dynein, cytoplasmic 1, intermediate chain 2 |
| Other gene symbols | DNCI2 IC2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0003777 | Microtubule motor activity | NAS | molecular_function |
| GO:0005737 | Cytoplasm | NAS | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005868 | Cytoplasmic dynein complex | IEA | cellular_component |
| GO:0005874 | Microtubule | IDA | cellular_component |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0007018 | Microtubule-based movement | IEA NAS | biological_process |
| GO:0008152 | Metabolic process | NAS | biological_process |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0031982 | Vesicle | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9403449679 | 0.0511759432 | 0.9999902473 | 0.4255930490 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1403262109 |
| GSE13712_SHEAR | Down | -0.3925788750 |
| GSE13712_STATIC | Down | -0.3577655398 |
| GSE19018 | Up | 0.2762334218 |
| GSE19899_A1 | Down | -0.5090010349 |
| GSE19899_A2 | Down | -0.6962352267 |
| PubMed_21979375_A1 | Down | -0.2073197093 |
| PubMed_21979375_A2 | Down | -0.6908604584 |
| GSE35957 | Up | 0.2873669387 |
| GSE36640 | Down | -0.1969463311 |
| GSE54402 | Down | -0.3694067770 |
| GSE9593 | Down | -0.1282361871 |
| GSE43922 | Down | -0.1062141713 |
| GSE24585 | Up | 0.1498920155 |
| GSE37065 | Up | 0.1811179319 |
| GSE28863_A1 | Down | -0.1687153952 |
| GSE28863_A2 | Up | 0.2995014150 |
| GSE28863_A3 | Down | -0.0792326687 |
| GSE28863_A4 | Down | -0.0552953127 |
| GSE48662 | Down | -0.1874848654 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1301-3p | MIMAT0005797 | MIRT036037 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 11500918 | Upregulation of the gene encoding a cytoplasmic dynein intermediate chain in senescent human cells |
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