HCSGD entry for DLX1

1. General information

Official gene symbolDLX1
Entrez ID1745
Gene full namedistal-less homeobox 1
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0000976Transcription regulatory region sequence-specific DNA bindingIEAmolecular_function
GO:0003682Chromatin bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0009954Proximal/distal pattern formationIEAbiological_process
GO:0021544Subpallium developmentIEAbiological_process
GO:0021766Hippocampus developmentIEAbiological_process
GO:0021882Regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitmentIEAbiological_process
GO:0021893Cerebral cortex GABAergic interneuron fate commitmentIEAbiological_process
GO:0042475Odontogenesis of dentin-containing toothIEAbiological_process
GO:0043524Negative regulation of neuron apoptotic processIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045746Negative regulation of Notch signaling pathwayIEAbiological_process
GO:0048706Embryonic skeletal system developmentIEAbiological_process
GO:0048715Negative regulation of oligodendrocyte differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.63688726870.13617540750.99999024730.7115929776

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0020506179
GSE13712_SHEARDown-0.1798810185
GSE13712_STATICDown-0.0638301766
GSE19018Up0.1864344709
GSE19899_A1Down-0.0500536740
GSE19899_A2Down-0.5851431539
PubMed_21979375_A1Up0.0057614649
PubMed_21979375_A2Down-0.4810085643
GSE35957Down-1.0070232919
GSE36640Down-0.6246605979
GSE54402Up0.0554906325
GSE9593Down-0.7571064374
GSE43922Up0.0519070066
GSE24585Up1.5577354680
GSE37065Down-0.0691545786
GSE28863_A1Down-0.0024741975
GSE28863_A2Up0.0516685505
GSE28863_A3Up0.1795869799
GSE28863_A4Up0.1009571456
GSE48662Down-0.3118705167

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT016270MicroarrayFunctional MTI (Weak)20304954
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.