HCSGD entry for DLG3
1. General information
| Official gene symbol | DLG3 |
|---|---|
| Entrez ID | 1741 |
| Gene full name | discs, large homolog 3 (Drosophila) |
| Other gene symbols | MRX MRX90 NEDLG SAP102 XLMR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001736 | Establishment of planar polarity | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005923 | Tight junction | IEA | cellular_component |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0008022 | Protein C-terminus binding | IEA | molecular_function |
| GO:0008285 | Negative regulation of cell proliferation | NAS | biological_process |
| GO:0010923 | Negative regulation of phosphatase activity | IDA | biological_process |
| GO:0019902 | Phosphatase binding | IDA | molecular_function |
| GO:0019903 | Protein phosphatase binding | IEA | molecular_function |
| GO:0030165 | PDZ domain binding | IEA | molecular_function |
| GO:0030426 | Growth cone | IEA | cellular_component |
| GO:0031625 | Ubiquitin protein ligase binding | IEA | molecular_function |
| GO:0032281 | Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex | IEA | cellular_component |
| GO:0035255 | Ionotropic glutamate receptor binding | IEA | molecular_function |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0043198 | Dendritic shaft | IEA | cellular_component |
| GO:0045197 | Establishment or maintenance of epithelial cell apical/basal polarity | IEA | biological_process |
| GO:0045202 | Synapse | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9904833593 | 0.0141179514 | 0.9999902473 | 0.2336706767 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1139044898 |
| GSE13712_SHEAR | Down | -0.4325772067 |
| GSE13712_STATIC | Down | -0.3067621328 |
| GSE19018 | Down | -0.2978540916 |
| GSE19899_A1 | Down | -0.1812417659 |
| GSE19899_A2 | Down | -1.3704640846 |
| PubMed_21979375_A1 | Down | -1.3803560317 |
| PubMed_21979375_A2 | Down | -0.8089112315 |
| GSE35957 | Down | -0.3948701573 |
| GSE36640 | Down | -2.0156882043 |
| GSE54402 | Down | -0.1226881108 |
| GSE9593 | Up | 0.1143328826 |
| GSE43922 | Down | -0.3646488809 |
| GSE24585 | Down | -0.0738753697 |
| GSE37065 | Up | 0.0835281920 |
| GSE28863_A1 | Down | -0.0202734328 |
| GSE28863_A2 | Up | 0.0377284888 |
| GSE28863_A3 | Up | 0.0247253493 |
| GSE28863_A4 | Up | 0.0365103807 |
| GSE48662 | Up | 0.1913630197 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017838 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040203 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045183 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
