HCSGD entry for POLR3H
1. General information
| Official gene symbol | POLR3H |
|---|---|
| Entrez ID | 171568 |
| Gene full name | polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) |
| Other gene symbols | RPC22.9 RPC8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003899 | DNA-directed RNA polymerase activity | IDA IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | IDA TAS | cellular_component |
| GO:0005666 | DNA-directed RNA polymerase III complex | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006139 | Nucleobase-containing compound metabolic process | IDA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006383 | Transcription from RNA polymerase III promoter | IDA TAS | biological_process |
| GO:0006385 | Transcription elongation from RNA polymerase III promoter | TAS | biological_process |
| GO:0006386 | Termination of RNA polymerase III transcription | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0032481 | Positive regulation of type I interferon production | TAS | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0051607 | Defense response to virus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2266814939 | 0.7250553398 | 0.9083944436 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2913130029 |
| GSE13712_SHEAR | Up | 0.1201307606 |
| GSE13712_STATIC | Down | -0.0573442862 |
| GSE19018 | Down | -0.1559002786 |
| GSE19899_A1 | Down | -0.0078669319 |
| GSE19899_A2 | Up | 0.4028783913 |
| PubMed_21979375_A1 | Up | 0.2403469542 |
| PubMed_21979375_A2 | Up | 0.5886485035 |
| GSE35957 | Up | 0.3141232891 |
| GSE36640 | Up | 0.1855412444 |
| GSE54402 | Up | 0.0836824723 |
| GSE9593 | Up | 0.2638252223 |
| GSE43922 | Up | 0.3973060532 |
| GSE24585 | Down | -0.5659516967 |
| GSE37065 | Down | -0.2888884430 |
| GSE28863_A1 | Down | -0.0501124731 |
| GSE28863_A2 | Down | -0.0330630247 |
| GSE28863_A3 | Down | -0.2601671401 |
| GSE28863_A4 | Up | 0.0469721397 |
| GSE48662 | Up | 0.0092561096 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1301-3p | MIMAT0005797 | MIRT035985 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038118 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039879 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042331 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042471 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043160 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043433 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30d-5p | MIMAT0000245 | MIRT047813 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
