HCSGD entry for NLRP6

1. General information

Official gene symbolNLRP6
Entrez ID171389
Gene full nameNLR family, pyrin domain containing 6
Other gene symbolsAVR CLR11.4 NALP6 NAVR NAVR/AVR PAN3 PYPAF5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005000Vasopressin receptor activityISSmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0007165Signal transductionISSbiological_process
GO:0007186G-protein coupled receptor signaling pathwayISSbiological_process
GO:0009617Response to bacteriumIEAbiological_process
GO:0031965Nuclear membraneIEAcellular_component
GO:0034122Negative regulation of toll-like receptor signaling pathwayIEAbiological_process
GO:0042060Wound healingIEAbiological_process
GO:0043124Negative regulation of I-kappaB kinase/NF-kappaB signalingIEAbiological_process
GO:0043409Negative regulation of MAPK cascadeIEAbiological_process
GO:0050727Regulation of inflammatory responseISSbiological_process
GO:0050777Negative regulation of immune responseIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.48799131110.87931449030.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0900438375
GSE13712_SHEARUp0.0321581047
GSE13712_STATICDown-0.0159854507
GSE19018Up0.1066236499
GSE19899_A1Up0.0852055211
GSE19899_A2Down-0.0595326807
PubMed_21979375_A1Up0.1431570550
PubMed_21979375_A2Down-0.0336065457
GSE35957Up0.1242124363
GSE36640Up0.0451793803
GSE54402Down-0.1285945638
GSE9593Up0.0493889011
GSE43922Up0.1299617800
GSE24585Up0.0472405359
GSE37065Down-0.0879293384
GSE28863_A1Up0.2753179879
GSE28863_A2Up0.1896838145
GSE28863_A3Up0.0695091722
GSE28863_A4Down-0.0664730665
GSE48662Down-0.0163685967

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.