HCSGD entry for CFD

1. General information

Official gene symbolCFD
Entrez ID1675
Gene full namecomplement factor D (adipsin)
Other gene symbolsADIPSIN ADN DF PFD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002576Platelet degranulationTASbiological_process
GO:0004252Serine-type endopeptidase activityIEAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0006956Complement activationTASbiological_process
GO:0006957Complement activation, alternative pathwayTASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008236Serine-type peptidase activityTASmolecular_function
GO:0030168Platelet activationTASbiological_process
GO:0031093Platelet alpha granule lumenTAScellular_component
GO:0045087Innate immune responseTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.05581345310.47607793780.51437881651.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0471309005
GSE13712_SHEARUp0.0697143019
GSE13712_STATICUp0.1790336525
GSE19018Down-0.0265632434
GSE19899_A1Down-0.2058032662
GSE19899_A2Down-0.6299652423
PubMed_21979375_A1Up0.1676286162
PubMed_21979375_A2Down-0.3018982663
GSE35957Down-0.2079801507
GSE36640Up0.1891376481
GSE54402Down-0.1902442731
GSE9593Down-0.1063196995
GSE43922Up0.1150204611
GSE24585Up0.5096809117
GSE37065Up0.1792436319
GSE28863_A1Up1.3127640600
GSE28863_A2Up0.0717445653
GSE28863_A3Up0.4473091511
GSE28863_A4Up0.0176285548
GSE48662Up0.2967046248

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

2-Aminobenzyl alcoholDB03058 EXPT02934
3,4-DichloroisocoumarinDB04459 EXPT01202

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.